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Preliminary Screening for Pharmacological Activities

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1     Reflex inhibition
   Central Stimulant
   Muscle relaxant
   Sympathomimetric
   Sympatholytic
   Parasympathomimetric
   Parasympatholytic
   Ganglion blocker
   Adrenergic neurone blocker
   CNS depressant
   Anaesthetic
   Vasodialator
   Vasoconstrictor
   Narcotic analgesic
Mouse P.O. Irwin test
2    Anti-aggressive Mouse P.O. Isolation-induced aggression
3    Anti-metrazol
Mouse P.O. Antagonism of metrazol convulsions
4    Anti-depressant
Mouse P.O. Antagonism of tetrabenazine ptosis
5    Analgesic
Rat P.O. Abdominal spasm test
6    Anti-parkinson
Mouse P.O. Anatagonism of reserpine catalepsy
7    Anorectic
Rat P.O. Decreased food consumption
8    Anti-hypertensive/pressor
Rat P.O. SHR rat
9    Cardiotropic
   beta-adrenergic stimulant
   beta-adrenergic blocker
   H2-receptor antagonist
   H2-receptor agonist
Guinea-pig In Vitro Isolated atrial preparation
10    Anti-arrhythmic
Mouse I.P. Prevention of chloroform arrhythmia
11    Inhibition of platelet aggregation
a. in vitro

b. In vivo


Human Human
Mouse


In vitro
In vitro
P.O.


ADP-induced
Collagern-induced
Arachidonic acid-induced pulmonary thromboembolism

12    Antihistaminic
   Anticholinergic
   Antiserotoninergic
   Spasmolytic
   Spasmogenic
Guinea-pig In vitro Isolated Ileum
13    Hypoglycaemic
Rat P.O. Serum glucose reduction
14    Diuretic
Rat P.O. Increase in urine excretion
15    Anti-inflammatory
Rat P.O. Carrageenan-induced oedema
16    Bronchodilator
Guinea-pig In vitro Lung perfusion
17    Antimicrobial/antifungal
In vitro Seven organisms
18    Immunostimulant/Immunosuppressant
Mouse P.O. Sheep RBC Haemolysis
19    Local anaesthetic
Mouse S.C. Tail pinch test