Special Task Cyclic Nucleotides

  • Adenosine- 2', 3'- cyclic monophosphorothioate, Rp- / endo isomer ( Rp-2',3'-cAMPS )Cat. No.: A 006
  • 2'- Amino- 2'- deoxyadenosine- 3', 5'- cyclic monophosphate ( 2'-NH2-cAMP ) Cat. No.: A 088
  • N6- (2- Aminoethyl)- 8- azidoadenosine- 3', 5'- cyclic monophosphate ( 6-AE-8-N3-cAMP )Cat. No.: A 101
  • 2- Aminopurine riboside- 3', 5'- monophosphate ( 2-NH2-cPuMP )Cat. No.: A 027
  • Arabinoadenosine- 3', 5'- cyclic monophosphate ( ara-cAMP )Cat. No.: A 076
  • 8- Azido- 1, N6- ethenoadenosine- 3', 5'- cyclic monophosphate ( 8-N3-ε-cAMP )Cat. No.: A 077
  • 8- Azido- N6- (2- [DY-547]- aminoethyl)adenosine- 3', 5'- cyclic monophosphate ( 8-N3-6-[DY-547]-AE-cAMP )Cat. No.: A 100
  • 8- Azido- N6- (6- [biotinyl]aminoethyl)adenosine- 3', 5'- cyclic monophosphate ( 8-N3-6-[Biotin]-AE-cAMP )Cat. No.: A 127
  • 8- Azidoadenosine- 3', 5'- cyclic monophosphate ( 8-N3-cAMP )Cat. No.: A 014
  • β- (4- Azidophenyl)- 1, N2- etheno- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( 4-N3-PET-8-Br-cGMP )Cat. No.: A 102
  • 8- (2- [ Biotinyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate ( 8-[Biotin]-AET-cAMP )Cat. No.: B 030
  • 8- (2- [ Biotinyl]aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[Biotin]-AET-cGMP )Cat. No.: B 025
  • N2- (6- [ Biotinyl]aminohexyl)guanosine- 3', 5'- cyclic monophosphate ( 2-[Biotin]-AH-cGMP )Cat. No.: B 032
  • 2- (6- [ Biotinyl]aminohexylamino)adenosine- 3', 5'- cyclic monophosphate ( 2-[Biotin]-AHA-cAMP )Cat. No.: B 041
  • 2- Chloroinosine- 3', 5'- cyclic monophosphate, sodium salt ( 2-Cl-cIMP )Cat. No.: C 029
  • 6- Chloropurine riboside- 3', 5'- cyclic monophosphate ( 6-Cl-cPuMP )Cat. No.: C 002
  • Cytidine- 3', 5'- cyclic monophosphate ( cCMP )Cat. No.: C 001
  • Cytidine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( cCMP-AM )Cat. No.: C 067
  • Cytidine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-cCMPS )Cat. No.: C 065
  • Cytidine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-cCMPS )Cat. No.: C 066
  • 2'- Deoxy- 2'- fluoroadenosine- 3', 5'- cyclic monophosphate ( 2'-F-cAMP )Cat. No.: D 073
  • 2'- Deoxyadenosine- 3', 5'- cyclic monophosphate ( 2'-dcAMP )Cat. No.: D 015
  • 2'- Deoxyguanosine- 3', 5'- cyclic monophosphate ( 2'-dcGMP )Cat. No.: D 020
  • N4, 2'- O- Dibutyrylcytidine- 3', 5'- cyclic monophosphate ( DB-cCMP )Cat. No.: D 075
  • 5, 6- Dichlorobenzimidazole riboside- 3', 5' - cyclic monophosphorothioate, Rp- isomer ( Rp-5,6-DCl-cBIMPS )Cat. No.: D 013
  • 5, 6- Dimethylbenzimidazole riboside- 3', 5'- cyclic monophosphate ( 5,6-DM-cBIMP )Cat. No.: D 001
  • 2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cAMP )Cat. No.: F 003
  • 2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cGMP )Cat. No.: F 004
  • 2'- O- (N- Methylanthraniloyl)adenosine- 3', 5'- cyclic monophosphate ( MANT-cAMP )Cat. No.: M 008
  • 2'- O- (N'- Methylanthraniloyl)cytidine- 3', 5'- cyclic monophosphate ( MANT-cCMP )Cat. No.: M 053
  • 2'- O- (N- Methylanthraniloyl)guanosine- 3', 5'- cyclic monophosphate ( MANT-cGMP )Cat. No.: M 009
  • 2'- O- Methylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-Me-cGMP )Cat. No.: M 036
  • 2'- O- Monosuccinyladenosine- 3', 5'- cyclic monophosphate ( 2'-O-MS-cAMP )Cat. No.: M 011
  • 2'- O- Monosuccinyladenosine- 3', 5'- cyclic monophosphate, tyrosylmethyl ester ( 2'-O-MS-TME-cAMP )Cat. No.: M 022
  • 2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-MS-cGMP )Cat. No.: M 015
  • 2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate, tyrosylmethyl ester ( 2'-O-MS-TME-cGMP )Cat. No.: M 023
  • 4- Nitrobenzimidazole riboside- 3', 5'- cyclic monophosphate ( 4-NO2-cBIMP )Cat. No.: N 007
  • 8- Nitroguanosine- 3', 5'- cyclic monophosphate ( 8-NO2-cGMP )Cat. No.: N 011
  • Thymidine- 3', 5'- cyclic monophosphate ( cTMP )Cat. No.: T 005
  • Uridine- 2', 3'- cyclic monophosphate ( 2',3'-cUMP )Cat. No.: U 004
  • Uridine- 3', 5'- cyclic monophosphate ( cUMP )Cat. No.: U 001
  • Xanthosine- 3', 5'- cyclic monophosphate ( cXMP )Cat. No.: X 001

     

  • Adenosine- 2', 3'- cyclic monophosphorothioate, Rp- / endo isomer ( Rp-2',3'-cAMPS )
       Tool for research on stereochemical requirements of 2‘,3‘-cAMP binding receptorse.
       Heaton & Eckstein, Nucleic Acids Res., 24, 850 - 853 (1996); Lowe & Thelin, J. Chem. Soc. Chem. Commun., 1947 - 1948 (1994).
    A 006 5 uM/ ~1.9 mg, 5 x 5 uM CAS No.: [118275-99-3]

    2'- Amino- 2'- deoxyadenosine- 3', 5'- cyclic monophosphate ( 2'-NH2-cAMP )
       2'-NH2-cAMP has a reactive amino group suitable for modification with fluorophores and other markers or spacers and can be used as ligand for affinity
       chromatography of cAMP and cGMP binding proteins that do not require an intact 2'-OH group.
    A 088 5 uM/ ~1.8 mg, 5 x 5 uM CAS No.: [85819-83-6]

    N6- (2- Aminoethyl)- 8- azidoadenosine- 3', 5'- cyclic monophosphate ( 6-AE-8-N3-cAMP )
       6-AE-8-N3-cAMP is a light sensitive analogue for photoaffinity labelling. It can be immobilized within a cyclic AMP binding site by illumination with UV light.
       The reactive amino group connected to position 6 of the adenine nucleobase can be used to form a conjugate with suitable reporter groups, such as
       fluorescent dyes or biotin, etc.
    A 010 1 uM/ ~0.4 mg, 5 x 1 uM CAS No.: [pending]

    2- Aminopurine riboside- 3', 5'- monophosphate ( 2-NH2-cPuMP )
       Fluorescent cyclic nucleotide, λexc 305 nm; λem 370 nm.
       Scheit, J. Carbohydr. Nucleosides, Nucleotides, 1, 385 - 399 (1974).
    A 027 5 uM/ ~1.8 mg, 5 x 5 uM CAS No.: [42467-66-3]

    Arabinoadenosine- 3', 5'- cyclic monophosphate ( ara-cAMP )
       Analogue of the second messenger cyclic AMP with an inverted configuration at the 2’- hydroxy group. Useful for receptor mapping studies and negative
       controls.
       Miller, Adv. Cyclic Nucleot. Res.,14, 335 - 344 (1981).
    A 076 5 uM/ ~1.8 mg, 5 x 5 uM CAS No.: [32465-18-2]

    8- Azido- 1, N6- ethenoadenosine- 3', 5'- cyclic monophosphate ( 8-N3-ε-cAMP )
       Nonfluorescent cAMP analogue, that can be used for labelling of cAMP receptors. Upon UV-light-induced immobilization the ethenoadenine moiety starts to
       fluoresce, providing a label for tracing the receptor protein.
       Keeler & Campbell, Biochem. Biophys. Res. Commun., 72, 575 - 80 (1976); Dreyfuss et al., Proc. Nat. Acad. Sci. USA, 75, 1199 - 1203 (1978).
    A 077 1 uM/ ~0.4 mg, 5 x 1 uM CAS No.: [60902-12-7]

    8- Azido- N6- (2- [DY-547]- aminoethyl)adenosine- 3', 5'- cyclic monophosphate ( 8-N3-6-[DY-547]-AE-cAMP )
       8-N3-6-[DY-547]-AE-cAMP is a light sensitive analogue for photoaffinity labelling. It can be immobilized within a cyclic AMP binding site by illumination with UV
       light. The fluorescent reporter group connected to position 6 of the adenine nucleobase can be excitated at 557 nm and emits with 574 nm.
    A 100 0.1 uM/ ~0.1 mg, 5 x 0.1 uM CAS No.: [pending]

    8- Azido- NN6- (6- [biotinyl]aminoethyl)adenosine- 3', 5'- cyclic monophosphate ( 8-N3-6-[Biotin]-AE-cAMP )
       Analogue for photoaffinity labelling of cAMP binding proteins which can be immobilized by UV light. The biotin label is connected to the 6-position of cyclic
       AMP via a 15 atom spacer.
    A 127 0.1 uM/ ~80 ug, 5 x 0.1 uM CAS No.: [pending]

    8- Azidoadenosine- 3', 5'- cyclic monophosphate ( 8-N3-cAMP )
       Analogue for photoaffinity labelling of cAMP binding proteins.
       Haley, Methods Enzymol., 46, 339 - 346 (1977).
    A 014 10 uM/ ~3.9 mg, 5 x 10 uM CAS No.: [31966-52-6]

    β- (4- Azidophenyl)- 1, N2- etheno- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( 4-N3-PET-8-Br-cGMP )
       Analogue for photoaffinity labelling of cGMP-responsive receptors, considered to be a isozyme-selective activator of cGMP-dependent protein kinase I α
       and β.
       Haley, Methods Enzymol., 46, 339 - 346 (1977).
    A 102 1 uM/ ~0.6 mg, 5 x 1 uM CAS No.: [pending]

    8- (2- [ Biotinyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate ( 8-[Biotin]-AET-cAMP )
       Cyclic AMP conjugated with a biotin label. The biotin label is connected to the 6-position of cyclic AMP via a 16 atom spacer.
    B 030 1 uM/ ~0.8 mg, 5 x 1 uM CAS No.: [pending]

    8- (2- [ Biotinyl]aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[Biotin]-AET-cGMP )
       Biotin conjugated to cyclic GMP. Biotin connected to the 8-position of cyclic GMP via a 15 atom spacer. A similar analogue but with a different position of
       attachment is described under Cat. No. B 032.
    B 025 1 uM/ ~0.8 mg, 5 x 1 uM CAS No.: [pending]

    N2- (6- [ Biotinyl]aminohexyl)guanosine- 3', 5'- cyclic monophosphate ( 2-[Biotin]-AH-cGMP )
       Biotin connected to the 2-position of cyclic GMP via a 19 atom spacer. A similar analog but with a different position of attachment is described under Cat.
       No. B 025.
    B 032 1 uM/ ~0.8 mg, 5 x 1 uM CAS No.: [pending]

    2- (6- [ Biotinyl]aminohexylamino)adenosine- 3', 5'- cyclic monophosphate ( 2-[Biotin]-AHA-cAMP )
      Cyclic AMP conjugated with a biotin label. The biotin label is connected to the 2-position of cyclic AMP via a 19 atom spacer.
    B 041 1 uM/ ~0.8 mg, 5 x 1 uM CAS No.: [pending]

    2- Chloroinosine- 3', 5'- cyclic monophosphate, sodium salt ( 2-Cl-cIMP )
       2-Cl-cIMP is an analogue of inosine-3',5'-cyclic monophosphate (cIMP, Cat. No. I 001) in which the hydrogen in position 2 is replaced by a chlorine atom.
      Hebert et al., J. Biol. Chem., 273, 5557 - 5565 (1998).
    C 029 5 uM/ ~1.9 mg, 5 x 5 uM CAS No.: [52301-30-1]

    6- Chloropurine riboside- 3', 5'- cyclic monophosphate ( 6-Cl-cPuMP )
       Analogue of cyclic AMP showing better membrane permeability and higher stability against phosphodiesterases. Suitable for nucleophilic substitutions at the
       6-position with affinity spacers or various labels.
       Michal et al., Pharmacol. Res. Commun., 6, 203 - 252 (1974).
    C 002 5 uM/ ~1.9 mg, 5 x 5 uM CAS No.: [94200-58-5]

    Cytidine- 3', 5'- cyclic monophosphate ( cCMP )
       Potential further second messenger.
       Newton, Nucleosides & Nucleotides 14, 743 - 747 (1995).
    C 001 50 uM/ ~16 mg, 5 x 50 uM CAS No.: [54925-33-6]

    Cytidine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( cCMP-AM )
       Membrane-permeant, metabolically activatable prodrug form of the potential further second messenger cyclic CMP. After permeation and metabolic activation
       by esterases the polar cCMP is released which is trapped inside the cell and subsequently metabolized quickly, resulting in a pulse-type signal.
    C 067 1 uM/ ~0.4 mg, 5 x 1 uM CAS No.: [pending]

    Cytidine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-cCMPS )
       Sulfur-modified form of the potential second messenger cyclic CMP and potential PDE-resistant inhibitor of cCMP-binding proteins.
       Eckstein & Kutzke, Tetrahedr. Lett., 27, 1657 -1660 (1986).
    C 065 1 uM/ ~0.3 mg, 5 x 1 uM CAS No.: [87063-79-4]

    Cytidine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-cCMPS )
       Sulfur-modified form of the potential second messenger cyclic CMP and potential PDE-resistant activator of cCMP-binding proteins.
       Eckstein & Kutzke, Tetrahedr. Lett., 27, 1657 -1660 (1986).
    C 066 5 uM/ ~1.7 mg, 5 x 5 uM CAS No.: [87063-81-8]

    2'- Deoxy- 2'- fluoroadenosine- 3', 5'- cyclic monophosphate ( 2'-F-cAMP )
       Protein kinase A inactive analogue of cyclic AMP with modified 2'- moiety for cAMP receptor mapping studies.
       Ikehara, Heterocycles 21, 75 - 90 (1984).
    D 073 5 uM/ ~1.8 mg, 5 x 5 uM CAS No.: [81356-81-2]

    2'- Deoxyadenosine- 3', 5'- cyclic monophosphate ( 2'-dcAMP )
       Protein kinase A inactive analogue of cyclic AMP with modified 2'- moiety for cAMP receptor mapping studies.
       Jastorff in Cyclic Nucleotides and Therapeutic Perspectives, Cehovic & Robison (eds.), pp. 85 - 95; Pergamon Press, Oxford/New York 1979.
    D 015 10 uM/ ~3.4 mg, 5 x 10 uM CAS No.: [93839-95-3]

    2'- Deoxyguanosine- 3', 5'- cyclic monophosphate ( 2'-dcGMP )
       Protein kinase G inactive analogue of cyclic GMP with modified 2'- moiety for cGMP receptor mapping studies.
       Hebert et al., J. Biol. Chem., 273, 5557 - 5565 (1998).
    D 020 10 uM/ ~3.5 mg, 5 x 10 uM CAS No.: [93919-42-7]

    N4, 2'- O- Dibutyrylcytidine- 3', 5'- cyclic monophosphate ( DB-cCMP )
       Membrane-permeant, metabolically activatable prodrug form of the potential further second messenger cyclic CMP.
       Yanagida et al., Neurosci. Lett., 114, 323 - 328 (1990).
    D 075 10 uM/ ~4.7 mg, 5 x 10 uM CAS No.: [64649-87-2]

    5, 6- Dichlorobenzimidazole riboside- 3', 5' - cyclic monophosphorothioate, Rp- isomer ( Rp-5,6-DCl-cBIMPS )
       Lipophilic and phosphodiesterase-resistant modulator of cAMP-dependent protein kinase.
       Dostmann et al., J. Biol. Chem., 265, 10484 - 10491 (1990).
    D 013 5 uM/ ~2.1 mg, 5 x 5 uM CAS No.: [120912-55-2]

    5, 6- Dichlorobenzimidazole riboside- 3', 5' - cyclic monophosphorothioate, Rp- isomer ( Rp-5,6-DCl-cBIMPS )
       Lipophilic and phosphodiesterase-resistant modulator of cAMP-dependent protein kinase.
       Dostmann et al., J. Biol. Chem., 265, 10484 - 10491 (1990).
    D 001 5 uM/ ~2.1 mg, 5 x 5 uM CAS No.: [120912-55-2]

    2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cAMP )
       Fluorescent, PKA-inactive cyclic AMP analogue. Fluorescent cAMP analogue; λexc 494 nm, λem 517 nm. Suitable for phosphodiesterase studies .
       Huang et al., J. Biomol. Screen., 7, 215 - 222 (2002).
    F 003 1 uM/ ~0.9 mg, 5 x 1 uM CAS No.: [pending]

    2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cGMP )
       Fluorescent, PKG-inactive cyclic GAMP analogue. Fluorescent cGMP analogue; λexc 494 nm, λem 517 nm. Suitable for phosphodiesterase studies .
       Huang et al., J. Biomol. Screen., 7, 215 - 222 (2002).
    F 004 1 uM/ ~0.9 mg, 5 x 1 uM CAS No.: [pending]

    2'- O- (N- Methylanthraniloyl)adenosine- 3', 5'- cyclic monophosphate ( MANT-cAMP )
       Fluorescent cyclic AMP analogue, suitable for phosphodiesterase studies. The compound shows a decrease in fluorescence when cleaved by PDE.
       λexc 350 nm, λem 445 nm;
       Hiratsuka, J. Biol. Chem., 257, 13354 - 13358 (1982); Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
    M 008 10 uM/ ~4.8 mg, 5 x 10 uM CAS No.: [83707-14-6]

    2'- O- (N'- Methylanthraniloyl)cytidine- 3', 5'- cyclic monophosphate ( MANT-cCMP )
       Fluorescent, membrane-permeant cyclic CMP analogue, potentially suitable for phosphodiesterase studies. The compound is expected to show a decrease
       in fluorescence when cleaved by PDE ; λexc 350 nm, λem 441 nm
       Hiratsuka, J. Biol. Chem., 257, 13354 - 13358 (1982).
    M 053 5 uM/ ~2.3 mg, 5 x 5 uM CAS No.: [pending]

    2'- O- (N- Methylanthraniloyl)guanosine- 3', 5'- cyclic monophosphate ( MANT-cGMP )
       Fluorescent cyclic GMP analogue, suitable for phosphodiesterase studies. The compound shows a decrease in fluorescence when cleaved by PDE.
       ; λexc 350 nm, λem 441 nm
       Hiratsuka, J. Biol. Chem., 257, 13354 - 13358 (1982); Johnson, Anal. Biochem., 162, 291 - 295 (1987); Brown et al., Biochem. Biophys. Res. Commun., 224, 684 - 689 (1996).
    M 009 10 uM/ ~5 mg, 5 x 10 uM CAS No.: [83707-15-7]

    2'- O- Methylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-Me-cGMP )
       Relatively polar analogue of cyclic GMP which activate neither protein kinase G nor Epac. 2'-O-Me-cGMP can be used as an inactive control in patch clamp
       applications. Also suitable for receptor mapping studies.
       Kang et. al., J. Physiol., 573, 595 - 609 (2006).
    M 036 5 uM/ ~1.9 mg, 5 x 5 uM CAS No.: [pending]

    2'- O- Monosuccinyladenosine- 3', 5'- cyclic monophosphate ( 2'-O-MS-cAMP )
       Cyclic AMP analogue, suitable for coupling of various ligands including proteins for ELISA.
       Horton et al., J. Immun. Methods, 155, 31 - 40 (1992).
    M 011 25 uM/ ~11 mg, 5 x 25 uM CAS No.: [36940-87-1]

    2'- O- Monosuccinyladenosine- 3', 5'- cyclic monophosphate, tyrosylmethyl ester ( 2'-O-MS-TME-cAMP )
       Cyclic AMP analogue, suitable for radio-iodination for use in cAMP immunoassays.
       Steiner et al., J. Biol. Chem., 247, 1106 - 1113 (1972).
    M 022 1 uM/ ~0.6 mg, 5 x 1 uM CAS No.: [104809-08-7]

    2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-MS-cGMP )
       Cyclic GMP analogue, suitable for coupling of various ligands including proteins for ELISA.
       Horton et al., J. Immun. Methods, 155, 31 - 40 (1992).
    M 015 25 uM/ ~12 mg, 5 x 25 uM CAS No.: [39118-26-8]

    2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate, tyrosylmethyl ester ( 2'-O-MS-TME-cGMP )
       Cyclic GMP analogue, suitable for radio-iodination for use in cGMP immunoassays.
       Steiner et al., J. Biol. Chem., 247, 1106 - 1113 (1972).
    M 023 1 uM/ ~0.6 mg, 5 x 1 uM CAS No.: [104872-93-7]

    4- Nitrobenzimidazole riboside- 3', 5'- cyclic monophosphate ( 4-NO2-cBIMP )
       Analogue of the second messenger cyclic AMP, lacking the purine ring nitrogens and offering a changed interaction potential at position 6 (adenine
       nomenclature). Suitable for receptor mapping studies.
       Van Lookeren Campagne et al., J. Biol. Chem., 265, 5847 ? 5854 (1990); Genieser et al., Carbohydr. Res., 234, 217 - 235 (1992).
    N 007 5 uM/ ~1.9 mg, 5 x 5 uM CAS No.: [127634-21-3]

    8- Nitroguanosine- 3', 5'- cyclic monophosphate ( 8-NO2-cGMP )
       The nitrated derivative of cGMP, 8-NO2-cGMP, is considered to play an important role in NO-mediated signal transduction. Formation of protein Cys-cGMP
       adducts by 8-NO2-cGMP was identified as a new post-translational modification of proteins, which is called S-guanylation.
       Sawa et al., Nat. Chem. Biol., 3, 727 - 735 (2007).
    N 011   CAS No.: [pending]

    Thymidine- 3', 5'- cyclic monophosphate ( cTMP )
       Cyclic nucleotide analogue for receptor mapping studies.
       Riegel et al., J. Exp. Biol., 201, 3411 - 3418 (1998).
    T 005 5 uM/ ~1.6 mg, 5 x 5 uM CAS No.: [76567-90-3]

    Uridine- 2', 3'- cyclic monophosphate ( 2',3'-cUMP )
       2‘,3‘-cUMP is a cyclic phosphate ester of uridine, where both, the 2‘- and the 3‘- hydroxy groups are esterified by phosphoric acid.
       Tomasz, Nucleic Acid Chem., 2, 875 - 879 (1978); Cheung & Abrash, Biochemistry, 3, 1883 - 1889 (1964).
    U 004 50 uM/ ~16 mg, 5 x 50 uM CAS No.: [15718-50-0]

    Uridine- 3', 5'- cyclic monophosphate ( cUMP )
       cUMP is a cyclic nucleotide with a pyrimidine nucleobase.
       Blecher et al., Arch. Biochem. Biophys., 142, 351 - 362 (1971); Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006).
    U 001 50 uM/ ~16 mg, 5 x 50 uM CAS No.: [56632-58-7]

    Xanthosine- 3', 5'- cyclic monophosphate ( cXMP )
       cXMP is a an analogue of cyclic GMP where the amino group in position 2 of the guanine nucleobase has been replaced by oxygen.
       Meyer et al., J. Cyclic Nucl. Res., 1, 159 - 167 (1975).
    X 001 5 uM/ ~1.8 mg, 5 x 5 uM CAS No.: [31319-70-7]