Nucleobases

  • 9- Acetyl- 6- chloroguanineCat. No.: A 135
  • 8- Aza- N6- nonanoyladenineCat. No.: A 134
  • 8- Bromoadenine ( 8-Br-Ade )Cat. No.: B 052
  • 8- Bromoguanine ( 8-Br-Gua )Cat. No.: B 058
  • 2- Chloroadenine ( 2-Cl-Ade )Cat. No.: C 040
  • 8- Chloroadenine ( 8-Cl-Ade )Cat. No.: C 023
  • 8- Chloroguanine ( 8-Cl-Gua )Cat. No.: C 027

     

  • 8- (4- Chlorophenylthio)adenine ( 8-pCPT-Ade )Cat. No.: C 069
  • 8- Chloroxanthine ( 8-Cl-X )Cat. No.: C 044
  • 1, N6- Ethenoadenine ( ε-Ade )Cat. No.: E 012
  • 8- Hydroxyadenine ( 8-OH-Ade )Cat. No.: H 007
  • 8- Hydroxyguanine ( 8-OH-Gua )Cat. No.: H 002
  • Ko-Libri Library of Nucleosides and NucleobasesCat. No.: K 001
  • 8- Nitroguanine ( 8-NO2-Gua )Cat. No.: N 003

     

  • 9- Acetyl- 6- chloroguanine
       This compound is not a regular product, but is offered under our * Nucleotide Treasury * program.
    A 135   CAS No.: [149376-70-5]

    8- Aza- N6- nonanoyladenine
       This compound is not a regular product, but is offered under our * Nucleotide Treasury * program.
    A 134   CAS No.: [4471-88-9]

    8- Bromoadenine ( 8-Br-Ade )
       Reactive precursor for synthesis of 8-modified adenine analogues.
       Park et al., Carcinogenesis, 10, 827 - 832 (1989).
    B 052 10 uM/ ~2.1mg, 5 x 10 uM CAS No.: [6974-78-3]

    8- Bromoguanine ( 8-Br-Gua )
       Reactive precursor for synthesis of 8-modified guanine analogues.
      
    B 058 10 uM/ ~2.3mg, 5 x 10 uM CAS No.: [3066-84-0]

    2- Chloroadenine ( 2-Cl-Ade )
       Potential cytotoxic metabolite of Cladribine, Clofarabine and 2- chloro cyclic AMP.
       Bontemps et al., Biochem Pharmacol., 59, 1237 - 1243 (2000).
    C 040 10 uM/ ~2.3mg, 5 x 10 uM CAS No.: [1839-18-5]

    8- Chloroadenine ( 8-Cl-Ade )
       Biomarker for analysis of chlorine stressed DNA / RNA .
       Whiteman et al., Biomarkers 4, 303 - 310 (1999).
    C 023 10 uM/ ~1.7mg, 5 x 10 uM CAS No.: [28128-28-1]

    8- Chloroguanine ( 8-Cl-Gua )
       Potential biomarker for analysis of chlorine stressed DNA / RNA and reactive precursor for synthesis of 8-modified guanines.
       This compound is also part of the Ko-Libri compound library (K 001).
    C 027 10 uM/ ~1.9mg, 5 x 10 uM CAS No.: [22052-03-5]

    8- (4- Chlorophenylthio)adenine ( 8-pCPT-Ade )
       Potential metabolite of the specific Epac activator 8-pCPT-2’-O-Me-cAMP (Cat. No. C 041).
       Laxman et al., Proc. Natl. Acad. Sci. USA, 103, 19194 - 19199 (2006).
    C 069 10 uM, 5 x 10 uM CAS No.: [22052-03-5]

    8- Chloroxanthine ( 8-Cl-X ))
       Potential metabolite of 8-chloro cyclic AMP, 8-chloroadenosine and other 8-chloroadenine containing structures.
       Cummings et al., J. Pharmaceut. Biomed. Anal., 12, 1289 - 1294 (1994); Han et al., J. Pharmacol. Exp. Ther., 265, 790 - 794 (1993).
    C 044 10 uM, 5 x 10 uM CAS No.: [13548-68-0]

    1, N6- Ethenoadenine ( ε-Ade )
       Fluorescent analogue of adenine.
       Holt et al., Carcinogenesis, 19, 1763 - 1769 (1998); Chen & Chang, Chem. Res. Toxicol., 17, 963 ? 971 (2004).
    E 012 10 uM/ ~1.6 mg, 5 x 10 uM CAS No.: [13875-63-3]

    8- Hydroxyadenine ( 8-OH-Ade )
       Reference for analysis of oxidative/radioactive stress RNA/DNA hydrolysates.
       Kaur & Halliwell, Biochem. J., 318, 21 - 22 (1996); Hartmann et al., Radiat. Phys. Chem., 76, 834 - 840 (2007).
    H 007 100 uM/ ~15 mg, 5 x 100 uM CAS No.: [21149-26-8]

    8- Hydroxyguanine ( 8-OH-Gua )
       Reference for analysis of oxidative stress RNA/DNA hydrolysates.
       Kaur & Halliwell, Biochem. J., 318, 21 - 23 (1996).
    H 002 100 uM/ ~17 mg, 5 x 100 uM CAS No.: [5614-64-2]

    Ko-Libri Library of Nucleosides and Nucleobases
       Compound library, 10 mM solution of nucleobases and nucleosides dissolved in 250 μl DMSO in 1.4 ml polypropylene vials in 96 (8 x 12) well
       polypropylene racks.
      
    K 001 48 x 250 ul  

    8- Nitroguanine ( 8-NO2-Gua )
       Reference for analysis of peroxynitrite-stressed DNA and RNA hydrolysates.
       Yermilov et al., Carcinogenesis, 16, 2045 - 2050 (1995); Halliwell, Mutation Res., 443, 37 - 52 (1999); Tretyakova et al., Mutation Res., 447, 287 - 303 (2000).
    N 003 100 uM/ ~17 mg, 5 x 100 uM CAS No.: [168701-80-2]