Nucleoside- 5'- triphosphates

  • Adenosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-ATP-メ-S )Cat. No.: A 039
  • Adenosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-ATP-メ-S )Cat. No.: A 040
  • Adenosine- 5'- O- (3- thiotriphosphate) ( ATP-ャ-S )Cat. No.: A 060
  • 2'- Amino- 2'- deoxyadenosine- 5'- O- triphosphate ( 2'-NH2-ATP )Cat. No.: A 113
  • 3'- Amino- 3'- deoxyadenosine- 5'- O- triphosphate ( 3'-NH2-ATP )Cat. No.: A 114
  • 8- Aminoadenosine- 5'- O- triphosphate ( 8-NH2-ATP )Cat. No.: A 115
  • 5- (3- Aminoallyl)- 2'- deoxyuridine- 5'- O- triphosphate ( AA-dUTP )Cat. No.: A 116
  • 5- (3- Aminoallyl)uridine- 5'- O- triphosphate ( AA-UTP )Cat. No.: A 117
  • N6- (4- Aminobutyl)adenosine- 5'- O- triphosphate ( 6-AB-ATP )Cat. No.: A 074
  • 2'- / 3'- O- (2- Aminoethylcarbamoyl)adenosine- 5'- O- triphosphate ( 2'-/3'-AEC-ATP / EDA-ATP )Cat. No.: A 072
  • 2- Aminopurine riboside- 5'- O- triphosphate ( 2-NH2-PuTP )Cat. No.: A 124
  • 8- Azidoadenosine- 5'- O- triphosphate ( 8-N3-ATP )Cat. No.: A 043
  • N6- Benzyladenosine- 5'- O- (3- thiotriphosphate) ( 6-Bn-ATP-ャ-S )Cat. No.: B 072
  • N6- Benzyladenosine- 5'- O- triphosphate ( 6-Bn-ATP )Cat. No.: B 024
  • 8- Bromo- 2'- deoxyadenosine- 5'- O- triphosphate ( 8-Br-dATP )Cat. No.: B 069
  • 8- Bromo- 2'- deoxyguanosine- 5'- O- triphosphate ( 8-Br-dGTP )Cat. No.: B 070
  • 8- Bromoadenosine- 5'- O- triphosphate ( 8-Br-ATP )Cat. No.: B 068
  • 8- Bromoguanosine- 5'- O- triphosphate ( 8-Br-GTP )Cat. No.: B 012
  • 2- Chloroadenosine- 5'- O- triphosphate ( 2-Cl-ATP )Cat. No.: C 039
  • 8- Chloroadenosine- 5'- O- triphosphate ( 8-Cl-ATP )Cat. No.: C 018
  • 6- Chloropurine riboside- 5'- O- triphosphate ( 6-Cl-PuTP )Cat. No.: C 049
  • N6- Cyclohexyladenosine- 5'- O- triphosphate ( 6-cHe-ATP )Cat. No.: C 084
  • N6- Cyclopentyladenosine- 5'- O- triphosphate ( 6-cPe-ATP )Cat. No.: C 062
  • 7- Deaza- 2'- deoxyadenosine- 5'- O- triphosphate ( 7-CH-dATP )Cat. No.: D 033
  • 7- Deazaadenosine- 5'- O- triphosphate ( 7-CH-ATP )Cat. No.: D 096
  • 2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- triphosphate ( ュ-dATP )Cat. No.: D 078
  • 2'- Deoxy- 2'- fluoroadenosine- 5'- O- triphosphate ( 2'-F-ATP )Cat. No.: D 074
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-dATP )Cat. No.: D 085
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-dGTP )Cat. No.: D 086
  • 2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dATP-メ-S )Cat. No.: D 006
  • 2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dATP-メ-S )Cat. No.: D 007
  • 2'- Deoxycytidine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dCTP-メ-S )Cat. No.: D 046
  • 2'- Deoxycytidine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dCTP-メ-S )Cat. No.: D 047
  • 2'- Deoxyguanosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dGTP-メ-S )Cat. No.: D 030
  • 2'- Deoxyguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dGTP-メ-S )Cat. No.: D 031
  • 3'- Deoxythymidine- 5'- O- triphosphate ( dTTP ) / 2', 3'- Dideoxythymidine- 5'- triphosphate ( ddTTP )Cat. No.: D 038
  • 2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dUTP-メ-S )Cat. No.: D 048
  • 2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dUTP-メ-S )Cat. No.: D 049
  • 2', 3'- Dideoxyadenosine- 5'- O- (1- thiotriphosphate), Rp- /Sp- isomers ( Rp-/Sp-ddATP-メ-S )Cat. No.: D 026
  • 2', 3'- Dideoxyadenosine- 5'- O- triphosphate ( ddATP )Cat. No.: D 018
  • 2', 3'- Dideoxycytidine- 5'- O- (1- thiotriphosphate), Rp-/Sp- isomers ( Rp-/Sp-ddCTP-メ-S )Cat. No.: D 027
  • 2', 3'- Dideoxycytidine- 5'- O- triphosphate ( ddCTP )Cat. No.: D 037
  • 2', 3'- Dideoxyguanosine- 5'- O- (1- thiotriphosphate), Rp-/Sp- isomers ( Rp-/Sp-ddGTP-メ-S )Cat. No.: D 025
  • 2', 3'- Dideoxyguanosine- 5'- O- triphosphate ( ddGTP )Cat. No.: D 019
  • 2', 3'- Dideoxythymidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers ( Rp-/Sp-ddTTP-メ-S )Cat. No.: D 029
  • 2', 3'- Dideoxyuridine- 5'- O- (1- thiotriphosphate), Rp- / Sp- isomers ( Rp-/Sp-ddUTP-メ-S )Cat. No.: D 028
  • 1, N6- Ethenoadenosine- 5'- O- triphosphate ( ュ-ATP )Cat. No.: E 004
  • Guanosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-GTP-メ-S )Cat. No.: G 014
  • Guanosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-GTP-メ-S )Cat. No.: G 015
  • Guanosine- 5'- O- (3- thiotriphosphate) ( GTP-ャ-S )Cat. No.: G 019
  • 2'-/3'- O- (N- Methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-ATP )Cat. No.: M 030
  • 2'-/3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-GTP )Cat. No.: M 032
  • 2'- / 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- [(モ, ャ)- imido]triphosphate ( MANT-GppNHp )Cat. No.: M 047
  • N6- (3- Methylbenzyl)adenosine- 5'- O- triphosphate ( 6-(3MeBn)-ATP )Cat. No.: M 025
  • N6- (1- Methylbutyl)adenosine- 5'- O- triphosphate ( 6-1MeBu-ATP )Cat. No.: M 027
  • N6- (2- Methylbutyl)adenosine- 5'- O- triphosphate ( 6-2MeBu-ATP )Cat. No.: M 029
  • 2- Methylthioadenosine- 5'- O- triphosphate ( 2-MeS-ATP )Cat. No.: M 021
  • N6- Phenyladenosine- 5'- O- triphosphate ( 6-Phe-ATP )Cat. No.: P 015
  • N6- (2- Phenylethyl)adenosine- 5'- O- (3- thiotriphosphate) ( 6-PhEt-ATP-ャ-S )Cat. No.: P 026
  • N6-(2- Phenylethyl)adenosine- 5'- O- triphosphate ( 6-PhEt-ATP )Cat. No.: P 012
  • Purine riboside- 5'- O- triphosphate ( PuTP )Cat. No.: P 009
  • Thymidine- 5'- O- (1-thiotriphosphate), Rp-isomer ( Rp-TTP-メ-S )Cat. No.: T 002
  • Thymidine- 5'- O- (1-thiotriphosphate), Sp-isomer ( Sp-TTP-メ-S )Cat. No.: T 003
  • Uridine- 5'- O- (1-thiotriphosphate), Rp- isomer ( Rp-UTP-メ-S )Cat. No.: U 002
  • Uridine- 5'- O- (1-thiotriphosphate), Sp- isomer ( Sp-UTP-メ-S )Cat. No.: U 003

     


  • Adenosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-ATP-メ-S )
       Useful for modulation of ATP-responsive receptors and determination of their stereospecificity. Competitive inhibitor of adenylate cyclase and substrate for
       ATPase reaction of gyrase
       Eckstein, Ann. Rev. Biochem., 54, 367 - 402 (1985).Cullis et al., Biochemistry, 36, 6059 - 6068 (1997).
    A 039 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [58976-49-1]

    Adenosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-ATP-メ-S )
       Useful for modulation of ATP-responsive receptors and determination of their stereospecificity . Increased metabolic stability compared to ATP. Accepted by
       RNA polymerase for incorporation of phosphorothioate into RNA.
       Eckstein, Ann. Rev. Biochem., 54, 367 - 402 (1985)
    A 040 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [35094-46-3]

    Adenosine- 5'- O- (3- thiotriphosphate) ( ATP-ャ-S )
       ATP analogue with increased metabolic stability. Useful for inhibition or activation of ATP-responsive receptors and determination of their stereospecificity
       and for thiophosphorylation of proteins.
       Chrysogelos et al., J. Biol. Chem., 258, 12624 - 12631 (1983); Allen et al., J. Am. Chem. Soc., 127, 5288 - 5289 (2007).
    A 060 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [93839-89-5]

    2'- Amino- 2'- deoxyadenosine- 5'- O- triphosphate ( 2'-NH2-ATP )
       Ligand for affinity chromatography and suitable for modification with fluorophores and other markers.
       Watanabe et al., J. Biochem., 90, 957 - 965 (1981).
    A 113 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [61468-88-0]

    3'- Amino- 3'- deoxyadenosine- 5'- O- triphosphate ( 3'-NH2-ATP )
       Ligand for affinity chromatography and suitable for modification with fluorophores and other markers.
       Watanabe et al., J. Biochem., 90, 957 - 965 (1981).
    A 114 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [4209-30-7]

    8- Aminoadenosine- 5'- O- triphosphate ( 8-NH2-ATP )
       Analogue of adenosine- 5¨- triphosphate suitable for receptor mapping purposes.
       Chen & Sheppard, J. Biol. Chem., 279, 40405 - 40411 (2004).
    A 115 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [35874-49-8]

    5- (3- Aminoallyl)- 2'- deoxyuridine- 5'- O- triphosphate ( AA-dUTP )
       Ligand for affinity chromatography and suitable for modification with fluorophores and other markers.
       Wang et al., Plant J., 32, 723 - 733 (2002).
    A 116 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [109921-28-0]

    5- (3- Aminoallyl)uridine- 5'- O- triphosphate ( AA-UTP )
       Ligand for affinity chromatography and suitable for modification with fluorophores and other markers.
       Aleksandrova et al., Bioorg. Khim., 13, 643 - 647 (1987); Wang, Diagn. Mol. Pathol., 14, 59 - 64 (2005).
    A 117 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [75221-88-4]

    N6- (4- Aminobutyl)adenosine- 5'- O- triphosphate ( 6-AB-ATP )
       Ligand for affinity chromatography and suitable for modification with fluorophores and other markers.
       Trayer et al., Biochem. J., 139, 609 - 623 (1974).
    A 074 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [280577-98-2]

    2'- / 3'- O- (2- Aminoethylcarbamoyl)adenosine- 5'- O- triphosphate ( 2'-/3'-AEC-ATP / EDA-ATP )
       Ligand for affinity chromatography and suitable for modification with fluorophores and other markers.
       Webb & Corrie, Biophys. J., 81, 1562 - 1569 (2001); Oiwa et al., J. Biochem., 123, 614 - 618 (1998).
    A 072 5 uM/ ~3.0 mg, 5 x 5 uM CAS No.: [173074-70-9]

    2- Aminopurine riboside- 5'- O- triphosphate ( 2-NH2-PuTP )
       Fluorescent triphosphate analogue, ルexc 305 nm; ルem 370 nm.
       McClure & Scheit, FEBS Lett., 32, 267 - 269 (1973).
    A 124 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [23001-60-7]

    8- Azidoadenosine- 5'- O- triphosphate ( 8-N3-ATP )
       Useful for photoaffinity labelling of ATP binding proteins and for incorporation into RNA for labeling purposes.
       Potter et al., Methods Enzymol., 91, 613 - 633 (1983); Haley & Hoffmann, Proc. Nat. Acad. Sci. USA, 71, 3367 - 3371 (1974).
    A 043 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [53696-59-6]

    N6- Benzyladenosine- 5'- O- (3- thiotriphosphate) ( 6-Bn-ATP-ャ-S )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Allen et al., Nature Meth., 4, 511 - 516 (2007) & J. Am. Chem. Soc., 127, 5288 - 5289 (2005)
    B 072 5 uM/ ~3.1 mg, 5 x 5 uM CAS No.: [pending]

    N6- Benzyladenosine- 5'- O- triphosphate ( 6-Bn-ATP )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999).
    B 024 5 uM/ ~3.0 mg, 5 x 5 uM CAS No.: [40922-97-2]

    8- Bromo- 2'- deoxyadenosine- 5'- O- triphosphate ( 8-Br-dATP )
       Analogue of dATP with changed syn/anti ratio for receptor mapping studies and starting structure for 8-modified dATP derivatives.
       Amarnath et al., Biochim. Biophys. Acta, 800, 207 - 213 (1984); Kamiya et al., J. Mol. Biol., 336, 843 - 850 (2004).
    B 069 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [92410-99-6]

    8- Bromo- 2'- deoxyguanosine- 5'- O- triphosphate ( 8-Br-dGTP )
       Analogue of dGTP with changed syn/anti ratio for receptor mapping studies and starting structure for 8-modified dGTP derivatives.
       Kamiya et al., J. Mol. Biol., 336, 843 - 850 (2004); Helfman et al., Biochemistry, 17, 1607 - 1611(1978).
    B 070 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [66891-23-4]

    8- Bromoadenosine- 5'- O- triphosphate ( 8-Br-ATP )
       Analogue of ATP with changed syn/anti ratio for receptor mapping studies and starting structure for 8-modified ATP derivatives.
       Maruta et al., Eur. J. Biochem., 256, 229 - 237(1998); Kwiatkowski & King, Biochemistry, 26, 7636 - 7640 (1987).
    B 068 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [23567-97-7]

    8- Bromoguanosine- 5'- O- triphosphate ( 8-Br-GTP )
       Analogue of GTP with changed syn/anti ratio for receptor mapping studies and starting structure for 8-modified GTP derivatives.
       Kapuler & Reich, Biochemistry, 10, 4050 - 4061 (1971); Uno et al., Biochim. Biophys. Acta, 228, 282 - 288 (1971).
    B 012 5 uM/ ~3.0 mg, 5 x 5 uM CAS No.: [23197-98-0]

    2- Chloroadenosine- 5'- O- triphosphate ( 2-Cl-ATP )
       P2Y purinoceptor agonist. Inhibits soluble guanylate cyclase.
       Ruiz-Stewart et al., Eur. J. Biochem., 269, 2186 - 2193 (2002).
    C 039 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [49564-60-5]

    8- Chloroadenosine- 5'- O- triphosphate ( 8-Cl-ATP )
       Corresponding triphosphate for research on 8-Cl-cAMP and 8-Cl-adenosine, respectively.
       Tagliaferri et al., Cancer Res., 48, 1642 - 1650 (1988); Gandhi et al., Cancer Res., 61, 5474 - 5479 (2001).
    C 018 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [185341-71-3]

    6- Chloropurine riboside- 5'- O- triphosphate ( 6-Cl-PuTP )
       ATP analogue with reactive chlorine function.
       Patzelt et al., Hoppe Seylers Z. Physiol. Chem., 355, 1237 (1974); Pares et al., Eur. J. Biochem., 105, 571 - 579 (1980).
    C 049 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [55673-61-5]

    N6- Cyclohexyladenosine- 5'- O- triphosphate ( 6-cHe-ATP )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Liu et al., Chemistry & Biology, 5, 91 - 101 (1998); Kapoor & Mitchison, Proc. Nat. Acad. Sci. USA, 96, 9106 - 9111 (1999).
    C 084 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [206978-73-6]

    N6- Cyclopentyladenosine- 5'- O- triphosphate ( 6-cPe-ATP )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999).
    C 062 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [189822-11-5]

    7- Deaza- 2'- deoxyadenosine- 5'- O- triphosphate ( 7-CH-dATP )
       Isosteric modification of dATP. Causes bending of corresponding oligonucleotides.
       Seela et al., Biochemistry, 28, 6193 - 6198 (1989).
    D 033 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [67460-15-5]

    7- Deazaadenosine- 5'- O- triphosphate ( 7-CH-ATP )
       Isosteric modification of ATP. Causes bending of corresponding oligonucleotides.
       Wieczorek et al., Bioorg. Med. Chem. Lett., 4, 987 - 994 (1994); Petrescu et al., Biochemistry, 21, 886 - 893(1982).
    D 096 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [10058-66-9]

    2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- triphosphate ( ュ-dATP )
       Fluorescent dATP analogue; ルexc 300 nm, ルem 415 nm.
       Revich et al., Carcinogenesis, 7, 1569 - 1576 (1986).
    D 078 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [81004-54-8]

    2'- Deoxy- 2'- fluoroadenosine- 5'- O- triphosphate ( 2'-F-ATP )
       Analogue of ATP for receptor mapping. 2¨-F-ATP can substitute for dATP using DNA polymerase メ and ャ, but not with DNA polymerase モ.
       Parker et al., Mol. Pharmacol., 34, 485 - 491 (1988); Ono et al., Nucleic Acids Res., 25, 4581 - 4588 (1997); Richardson et al., Biochem. Pharmacol., 59, 1045 - 1052 (2000).
    D 074 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [73449-07-7]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-dATP )
       Fluorescent analogue of 2'- deoxyadenosine- 5¨- triphosphate, useful for research into dATP-dependent receptor proteins. (ルexc 355 nm; ルem 448 nm)
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983). Nomanbhoy & Schimmel, Bioorg. Med. Chem. Lett., 11, 1485 - 1491 (2001).
    D 085 5 uM/ ~3.1 mg, 5 x 5 uM CAS No.: [128113-53-1]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-dGTP )
       Fluorescent analogue of 2'- deoxyguanosine- 5¨- triphosphate, useful for research into 5¨-dGTP-dependent receptor proteins. (ルexc 355 nm; ルem 448 nm)
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983).
    D 086 5 uM/ ~3.2 mg, 5 x 5 uM CAS No.: [124615-99-2]

    2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dATP-メ-S )
       Useful for inhibition or activation of dATP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dATP.
       Not accepted by DNA polymerase.
       Romaniuk et al., J. Biol. Chem., 257, 7684 - 7688 (1982).
    D 006 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [87358-15-4]

    2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dATP-メ-S )
       Useful for modulation of dATP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dATP. Accepted by
       DNA polymerase for incorporation of phosphorothioate into DNA.
       Ronaghi et al., Science, 281, 363 - 365 (1998), Gharizadeh et al., Anal. Biochem., 301, 82 - 90 (2002).
    D 007 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [80875-87-2]

    2'- Deoxycytidine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dCTP-メ-S )
       Useful for modulation of dCTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dCTP. Not
        accepted by DNA polymerases.
       Abbotts et al., J. Biol. Chem., 263, 15094 - 15103 (1988).
    D 046 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [80951-76-4]

    2'- Deoxycytidine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dCTP-メ-S )
       Useful for modulation of dCTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dCTP. Accepted
       by DNA polymerase for incorporation of phosphorothioate into DNA.
       Abbotts et al., J. Biol. Chem., 263, 15094 - 15103 (1988); Nakamaye et al., Nucl. Acids Res., 16, 9947 - 9959 (1988); Nyren et al., Anal. Biochem., 244, 367 - 373 (1997);
       Choi et al., J. Biol. Chem., 281, 38244 - 38256 (2006).
    D 047 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [80951-75-3]

    2'- Deoxyguanosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dGTP-メ-S )
       Useful for modulation of dGTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dGTP. Not
       accepted by DNA polymerases.
       Abbotts et al., J. Biol. Chem., 263, 15094 - 15103 (1988); Kunkel et al., Proc. Natl. Acad. Sci. USA, 78, 6734 - 6738 (1981).
    D 030 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [80902-29-0]

    2'- Deoxyguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dGTP-メ-S )
       Useful for modulation of dGTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dGTP. Accepted by
       DNA polymerase for incorporation of phosphorothioate into DNA.
       Abbotts et al., J. Biol. Chem., 263, 15094 - 15103 (1988); Nakamaye et al., Nucl. Acids Res., 16, 9947 - 9959 (1988); Nyren et al., Anal. Biochem., 244, 367 - 373 (1997).
    D 031 5 uM/ ~2.6 mg, 5 x 5 uM CAS No.: [80902-28-9]

    3'- Deoxythymidine- 5'- O- triphosphate ( dTTP ) / 2', 3'- Dideoxythymidine- 5'- triphosphate ( ddTTP )
       Inhibits DNA polymerase I- dependent chain elongation.
       Sanger et al., Proc. Natl. Acad. Sci. USA, 74, 5463 - 5467 (1977).
    D 038 5 uM/ ~2.3 mg, 5 x 5 uM CAS No.: [128524-26-5]

    2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-dUTP-メ-S )
       C9H15N2O13P3S; MW 484.2 (free acid); ルmax 260 nm; ュ 10000; sodium salt, purity > 95% HPLC.
       Bergman et al., FEBS Lett., 441, 327 - 330 (1998).
    D 048 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [170428-85-0]

    2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-dUTP-メ-S )
       C9H15N2O13P3S; MW 484.2 (free acid); ルmax 260 nm; ュ 10000; sodium salt, purity > 95% HPLC.
       Bergman et al., FEBS Lett., 441, 327 - 330 (1998).
    D 049 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [170428-85-0]

    2', 3'- Dideoxyadenosine- 5'- O- triphosphate ( ddATP )
       Inhibits DNA polymerase I- dependent chain elongation.
       Sanger et al., Proc. Natl. Acad. Sci. USA, 74, 5463 - 5467 (1977).
    D 018 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [132619-65-9]

    2', 3'- Dideoxycytidine- 5'- O- (1- thiotriphosphate), Rp-/Sp- isomers ( Rp-/Sp-ddCTP-メ-S )
       Useful in mass spectrometry genotyping.
       Sauer et al., Nucleic Acids Res., 28 (5), e13 (2000).
    D 027 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [154771-49-0]

    2', 3'- Dideoxycytidine- 5'- O- triphosphate ( ddCTP )
       Inhibits DNA polymerase I- dependent chain elongation.
       Sanger et al., Proc. Natl. Acad. Sci. USA, 74, 5463 - 5467 (1977).
    D 037 5 uM/ ~2.3 mg, 5 x 5 uM CAS No.: [132619-66-0]

    2', 3'- Dideoxyguanosine- 5'- O- (1- thiotriphosphate), Rp-/Sp- isomers ( Rp-/Sp-ddGTP-メ-S )
       Useful in mass spectrometric genotyping.
       Sauer et al., Nucleic Acids Res., 28 (5), e13 (2000).
    D 025 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [154771-50-3]

    2', 3'- Dideoxyguanosine- 5'- O- triphosphate ( ddGTP )
       Inhibits DNA polymerase I- dependent chain elongation.
       Sanger et al., Proc. Natl. Acad. Sci. USA, 74, 5463 - 5467 (1977).
    D 019 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [68726-28-3]

    2', 3'- Dideoxythymidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers ( Rp-/Sp-ddTTP-メ-S )
       Useful in mass spectrometric genotyping.
       Sauer et al., Nucleic Acids Res., 28 (5), e13 (2000).
    D 029 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [154771-48-9]

    2', 3'- Dideoxyuridine- 5'- O- (1- thiotriphosphate), Rp- / Sp- isomers ( Rp-/Sp-ddUTP-メ-S )
       Useful in mass spectrometric genotyping.
    D 028 5 uM/ ~2.3 mg, 5 x 5 uM CAS No.: [pending]

    1, N6- Ethenoadenosine- 5'- O- triphosphate ( ュ-ATP )
       Fluorescent ATP analogue; ルexc 300 nm, ルem 415 nm.
       Yip et al., Tetrahedron Lett., 33, 3087 - 3090 (1973).
    E 004 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [60777-99-3]

    Guanosine- 5'- O- (1- thiotriphosphate), Rp- isomer ( Rp-GTP-メ-S )
       Modulator of GTP binding proteins with often increased metabolic stability. Useful for characterization of GTP-responsive receptors and determination of their
       stereospecificity.
       Koch et al., J. Biol. Chem., 265, 9659 - 9663 (1990); Von zur Muehlen et al., Int. Arch. Allergy Appli. Immunol., 94, 74 - 75 (1991).
    G 014 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [81570-50-5]

    Guanosine- 5'- O- (1- thiotriphosphate), Sp- isomer ( Sp-GTP-メ-S )
       Useful for modulation of GTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to GTP. Accepted by
       RNA polymerase for incorporation of phosphorothioate into RNA, by guanylate cyclase for cyclisation to Sp-cGMPS and by tubulinModulator of GTP binding
       proteins with often increased metabolic stability.
       Eckstein, Ann. Rev. Biochem., 54, 367 - 402 (1985). Xu et al., Biochim. Biophys. Acta, 1383, 111 - 122 (1998).
    G 015 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [81570-51-6]

    Guanosine- 5'- O- (3- thiotriphosphate) ( GTP-ャ-S )
       GTP analogue with increased metabolic stability which activates G proteins.
       Gilman, Ann. Rev. Biochem., 56, 615 - 649 (1987).
    G 019 5 uM/ ~2.7 mg, 5 x 5 uM CAS No.: [37589-80-3]

    2'-/3'- O- (N- Methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-ATP )
       Fluorescent analogue of adenosine- 5¨- triphosphate, useful for research into ATP-dependent receptor proteins. Potent inhibitor of adenylate cyclase. ルexc 355 nm; ルem 448 nm;
       Mocz et al., Biochemistry, 37, 9862 - 9869 (1998); Woodward et al., Biochemistry, 30, 422 - 430 (1991). Mou et al., J. Biol. Chem., 280, 7253 - 7261 (2001);
       Gilman, Ann. Rev. Biochem., 56, 615 - 649 (1987).
    M 030 5 uM/ ~3.2 mg, 5 x 5 uM CAS No.: [151481-86-6]

    2'-/3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-GTP )
       Fluorescent analogue of guanosine- 5¨- triphosphate, useful for research into GTP-dependent receptor proteins. Potent inhibitor of adenylate cyclase.
       ルexc 355 nm; ルem 448 nm;
       Gille & Seifert, J. Biol. Chem., 278, 12672 - 12679 (2003).
    M 032 5 uM/ ~3.3 mg, 5 x 5 uM CAS No.: [148821-03-8]

    2'- / 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- [(モ, ャ)- imido]triphosphate ( MANT-GppNHp )
       Fluorescent, analogue of the hydrolysis-resistant guanosine- 5'- O- [(モ, ャ)- imido]triphosphate, useful for research into GTP- dependent receptor proteins.
       Potent inhibitor of adenylate cyclase. ルexc 355 nm; ルem 448 nm;
       Herrmann et al., J. Biol. Chem., 270, 2901 - 2905 (1994); Gille. & Seifert, J. Biol. Chem., 278, 12672 - 12679 (2003); Zhang et al., J. Biol. Chem. 280, 33200 - 33205 (2005).
    M 047 1 uM/ ~0.7 mg, 5 x 1 uM CAS No.: [148821-01-6]

    N6- (3- Methylbenzyl)adenosine- 5'- O- triphosphate ( 6-(3MeBn)-ATP )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Liu et al., Bioorg. Med. Chem., 6, 1219 - 1226 (1998); Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999); Liu et al., Biochemistry, 39, 14400 - 14408 (2000).
    M 025 5 uM/ ~3.1 mg, 5 x 5 uM CAS No.: [215321-95-2]

    N6- (1- Methylbutyl)adenosine- 5'- O- triphosphate ( 6-1MeBu-ATP )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Kumar et al., Methods, 32, 389 - 397 (2004); Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999).
    M 027 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [252889-13-7]

    N6- (2- Methylbutyl)adenosine- 5'- O- triphosphate ( 6-2MeBu-ATP )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Zhou et al., J. Physiology, 569, 447 - 457 (2005); Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999).
    M 029 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [252889-14-8]

    2- Methylthioadenosine- 5'- O- triphosphate ( 2-MeS-ATP )
       Agonist of the P2Y purinoceptor. Inhibits soluble guanylate cyclase.
       Ruiz-Stewart et al., Eur. J. Biochem., 269, 2186 - 2193 (2002).
    M 021 5 uM/ ~2.8 mg, 5 x 5 uM CAS No.: [43170-89-4]

    N6- Phenyladenosine- 5'- O- triphosphate ( 6-Phe-ATP )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999).
    P 015 5 uM/ ~2.9 mg, 5 x 5 uM CAS No.: [105740-47-4]

    N6- (2- Phenylethyl)adenosine- 5'- O- (3- thiotriphosphate) ( 6-PhEt-ATP-ャ-S )
       Analogue useful for specific interaction with modified receptor proteins (chemical genetics).
       Allen et al., Nature Meth., 4, 511 - 516 (2007) & J. Am. Chem. Soc., 127, 5288 - 5289 (2005).
    P 026 5 uM/ ~3.1 mg, 5 x 5 uM CAS No.: [pending]

    N6-(2- Phenylethyl)adenosine- 5'- O- triphosphate ( 6-PhEt-ATP )
       Analogue useful for specific interaction with modified receptor proteins.
       Gillespie et al., J. Biol. Chem., 274, 31373 - 31381 (1999).
    P 012 5 uM/ ~3.1 mg, 5 x 5 uM CAS No.: [181705-62-4]

    Purine riboside- 5'- O- triphosphate ( PuTP )
       Analogue useful for ATP receptor mapping. Competes with ATP and thus could be the reason for purine riboside toxicity.
       Kozlowska et al., Toxicol. Lett., 104, 171 - 181 (1999).
    P 009 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [23197-96-8]

    Thymidine- 5'- O- (1-thiotriphosphate), Rp-isomer ( Rp-TTP-メ-S )
       Useful for modulation of TTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to TTP. Not accepted
       by DNA polymerases.
       Abbotts et al., J. Biol. Chem., 263, 15094 - 15103 (1988)..
    T 002 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [83199-35-3]

    Thymidine- 5'- O- (1-thiotriphosphate), Sp-isomer ( Sp-TTP-メ-S )
       Useful for inhibition or activation of TTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to TTP.
       Accepted by DNA polymerase for incorporation of phosphorothioate into DNA.
       Abbotts et al., J. Biol. Chem., 263, 15094 - 15103 (1988); Nakamaye et al., Nucl. Acids Res., 16, 9947 - 9959 (1988); Nyren et al., Anal. Biochem., 244, 367 - 373 (1997).
    T 003 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [83199-32-0]

    Uridine- 5'- O- (1-thiotriphosphate), Rp- isomer ( Rp-UTP-メ-S )
       Useful for modulation of UTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to UTP. Not accepted
       by RNA polymerases.
       Sheu et al., Biochemistry, 18, 5548 - 5556 (1979)
    U 002 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [71214-30-4]

    Uridine- 5'- O- (1-thiotriphosphate), Sp- isomer ( Sp-UTP-メ-S )
       Useful for modulation of UTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to UTP. Accepted
       by RNA polymerases.
       Armstrong et al., Biochemistry, 18, 4121 - 4123 (1979).
    U 003 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [71214-29-4]