Nucleoside- 5'- monophosphates

  • Adenosine- 5'- O- monophosphorothioate ( 5'- AMPS )Cat. No.: A 005
  • Adenosine- 5'- O- phosphosulfate ( APS )Cat. No.: A 061
  • 2- Amino- 6- chloropurine riboside- 5'- O- monophosphate ( 2-NH2-6-Cl-5'-PuMP )Cat. No.: A 084
  • 5- Aminoimidazole- 4- carboxamide- 1- ß- D- ribofuranoside- 5'- O- monophosphate ( AICAR-5'-MP / ZMP )Cat. No.: A 105
  • 8- Bromoadenosine- 5'- O- monophosphate ( 8-Br-5'-AMP )Cat. No.: B 066
  • 8- Bromoguanosine- 5'- O- monophosphate ( 8-Br-5'-GMP )Cat. No.: B 057
  • 2- Chloroadenosine- 5'- O- monophosphate ( 2-Cl-5'-AMP )Cat. No.: C 054
  • 8- Chloroadenosine- 5'- O- monophosphate ( 8-Cl-5'-AMP )Cat. No.: C 016
  • 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 5'- O- monophosphate ( 8-pCPT-2'-O-Me-5'-AMP )Cat. No.: C 078
  • 6- Chloropurine riboside- 5'- O- monophosphate ( 6-Cl-5'-PuMP )Cat. No.: C 032
  • N6- Cyclopentyladenosine- 5'- O- monophosphate ( 6-cPe-AMP )Cat. No.: C 089
  • Cytidine- 5'- O- monophosphorothioate ( 5'-CMPS )Cat. No.: C 053
  • 7- Deaza- 2'- deoxyadenosine- 5'- O- monophosphate ( 7-CH-5'-dAMP/dTuMP )Cat. No.: D 058
  • 7- Deazaadenosine- 5'- O- monophosphate ( 7-CH-5'-AMP/TuMP )Cat. No.: D 032
  • 2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- monophosphate ( ε-5'-dAMP )Cat. No.: D 077
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-dAMP)Cat. No.: D 081
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-dGMP )Cat. No.: D 082
  • 2'- Deoxyadenosine- 5'- O- monophosphorothioate ( 5'-dAMPS )Cat. No.: D 003
  • 2'- Deoxycytidine- 5'- O- monophosphorothioate ( 5'-dCMPS )Cat. No.: D 059
  • 2'- Deoxyguanosine- 5'- O- monophosphorothioate ( 5'-dGMPS )Cat. No.: D 056
  • 2'- Deoxyinosine- 5'- O- monophosphorothioate ( 5'-dIMPS )Cat. No.: D 060
  • 2'- Deoxyuridine- 5'- O- monophosphosphorothioate ( 5'-dUMPS )Cat. No.: D 057
  • 1, N6- Ethenoadenosine- 5'- O- monophosphate ( ε-5'-AMP )Cat. No.: E 005
  • Guanosine- 5'- O- monophosphorothioate ( 5'-GMPS )Cat. No.: G 018
  • N6- Methyladenosine- 5'- O- monophosphate ( N6-5'-Me-AMP )Cat. No.: M 038
  • 2'-/3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-AMP )Cat. No.: M 037
  • 2'-, 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-GMP )Cat. No.: M 042
  • 2- Methylthioadenosine- 5'- O- monophosphate ( 2-MeS-5'-AMP )Cat. No.: M 031
  • Purine riboside- 5'- O- monophosphate ( 5'-PuMP )Cat. No.: P 011
  • Thymidine- 5'- O- monophosphorothioate ( 5'-TMPS )Cat. No.: T 004
  • Uridine- 5'- O- monophosphorothioate ( 5'-UMPS )

     


  • Adenosine- 5'- O- monophosphorothioate ( 5'- AMPS )
       Substrate, competitive inhibitor or regulator of enzymes that interact with adenosine- 5'- monophosphate. Can be linked to structures with SH-groups via a
       disulfide bond. P2y11 receptor antagonist.
       Swennen et al., Biochem. Biophys. Res. Commun., 348, 1194 - 1199 (2006).
    A 005 50 uM/ ~18mg, 5 x 50 uM CAS No.: [19341-57-2]

    Adenosine- 5'- O- phosphosulfate ( APS )
       APS is a sulfate ester of adenosine- 5'- O- monophosphate (5'-AMP) and represents an active form of sulfate.
       Hofgen et al., Amino Acids, 20, 291 - 299 (2001); Eriksson et al., Anal. Biochem., 293, 67 - 70 (2001); Ronaghi et al., Science, 281, 363 - 365 (1998).
    A 061 10 uM/ ~4.3mg, 5 x 10 uM CAS No.: [102029-95-8]

    2- Amino- 6- chloropurine riboside- 5'- O- monophosphate ( 2-NH2-6-Cl-5'-PuMP )
       Analogue of adenosine- 5'- O- monophosphate, useful as precursor for 6-modified 5'-AMP derivatives.
    A 084 5 uM/ ~1.9mg, 5 x 5 uM CAS No.: [pending]

    5- Aminoimidazole- 4- carboxamide- 1- ß- D- ribofuranoside- 5'- O- monophosphate ( AICAR-5'-MP / ZMP )
       Analogue of AICA-riboside that mimics AMP and acts as an activator of AMP-activated protein kinase.
       Fryer et al. Biochem. J., 363, 167 - 174, (2002); Musi & Goodyear, Acta Physiol. Scand., 178, 337 - 345 (2003).
    A 105 10 uM/ ~4.3mg, 5 x 10 uM CAS No.: [3031-94-5]

    8- Bromoadenosine- 5'- O- monophosphate ( 8-Br-5'-AMP )
       Analogue of 5’-AMP with changed syn/anti ratio for receptor mapping studies and as starting structure for 8-modified 5’-AMP derivatives.
       Lascu et al., Biochemistry, 18, 4818 - 4826 (1979); Carr & Thompson, J. Comp. Physiol., 153, 47 - 53 (1983).
    B 066 10 uM/ ~4.3mg, 5 x 10 uM CAS No.: [23567-96-6]

    8- Bromoguanosine- 5'- O- monophosphate ( 8-Br-5'-GMP )
       Analogue of 5’-GMP with changed syn/anti ratio for receptor mapping studies and as starting structure for 8-modified 5’-GMP derivatives.
       Collier & Wagner, Org. Biomol. Chem., 4, 4526 - 4532 (2006); Lassota et al., Z. Naturforsch., 39C, 55 - 63 (1984).
    B 057 10 uM/ ~4.4mg, 5 x 10 uM CAS No.: [21870-09-7]

    2- Chloroadenosine- 5'- O- monophosphate ( 2-Cl-5'-AMP )
       Analogue of 5'-AMP with a reactive chlorine for introduction of modifications in position 2 of the adenine nucleobase.
       Gough et al., J. Med. Chem., 12, 494 - 498 (1969).
    C 054 10 uM/ ~3.8mg, 5 x 10 uM CAS No.: [21466-01-3]

    8- Chloroadenosine- 5'- O- monophosphate ( 8-Cl-5'-AMP )
       Potential metabolite of 8- chloroadenosine- 3', 5'- cyclic monophosphate (8-Cl-cAMP).
       Han et al., J. Pharmacol. Exper. Ther., 265, 790 - 794 (1992); Halgren et al., Blood, 92, 2893 - 2898 (1998).
    C 016 5 uM/ ~1.9mg, 5 x 5 uM CAS No.: [37676-40-7]

    8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 5'- O- monophosphate ( 8-pCPT-2'-O-Me-5'-AMP )
       Potential metabolite of the specific Epac activator 8-pCPT-2’-O-Me-cAMP (Cat. No C 041).
       Laxman et al., Proc. Natl. Acad. Sci. USA, 103,19194 - 19199 (2006).
    C 078 5 uM/ ~2.5mg, 5 x 5 uM CAS No.: [pending]

    6- Chloropurine riboside- 5'- O- monophosphate ( 6-Cl-5'-PuMP )
       Analogue of 5'-AMP with reactive chlorine for introduction of modifications in position 6 of the adenine nucleobase.
       Pares et al., Eur. J. Biochem., 105, 571 - 579 (1980).
    C 032 10 uM/ ~3.7mg, 5 x 10 uM CAS No.: [5843-59-4]

    N6- Cyclopentyladenosine- 5'- O- monophosphate ( 6-cPe-AMP )
       N6-modified analogue of adenosine-5'-O-monophosphate (AMP).
       Mlejnek & Dolezel, Toxicol. In Vitro, 19, 985 - 990 (2005).
    C 089 5 uM/ ~2.1mg, 5 x 5 uM CAS No.: [117778-38-8]

    Cytidine- 5'- O- monophosphorothioate ( 5'-CMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with cytidine- 5'- monophosphate. Can be linked to structures with SH-groups
       via a disulfide bond.
       Basu et al., Meth. Mol. Biol., 252, 57 -75 (2004).
    C 053 5 uM/ ~1.7mg, 5 x 5 uM CAS No.: [47151-76-8]

    7- Deaza- 2'- deoxyadenosine- 5'- O- monophosphate ( 7-CH-5'-dAMP/dTuMP )
       Synonym: 2’- Deoxytubercidin- 5'- O- monophosphate. Potential substrate, competitive inhibitor or regulator of enzymes that interact with 2’- deoxyadenosine
       - 5'- monophosphate.
       Seela & Kehne, Tetrahedron 41, 5387 - 5392 (1985).
    D 058 5 uM/ ~1.7mg, 5 x 5 uM CAS No.: [103078-56-4]

    7- Deazaadenosine- 5'- O- monophosphate ( 7-CH-5'-AMP/TuMP )
       Synonym: Tubercidin- 5'- O- monophosphate. Potential substrate, competitive inhibitor or regulator of enzymes that interact with adenosine- 5'-
       monophosphate.
       Minelli et al., Mol. Genet. Metab., 66, 49 - 55 (1999).
    D 032 10 uM/ ~3.5mg, 5 x 10 uM CAS No.: [16719-46-3]

    2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- monophosphate ( ε-5'-dAMP )
       Fluorescent analogue of 2’- deoxyadenosine- 5'- monophosphate; λexc 300 nm, λem 415 nm.
       Vandenbunner et al., Proc. Nat. Acad. Sci. USA, 73, 2696 - 2700 (1976); Chabbert et al., J. Biol. Chem., 266, 5395 - 5400 (1991).
    D 077 5 uM/ ~1.8mg, 5 x 5 uM CAS No.: [60508-81-8]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-dAMP)
       Fluorescent analogue of 2'- deoxyadenosine- 5’- monophosphate, useful for research into 5’-dAMP-dependent receptor proteins. The MANT fluorophore has
       a certain sensitivity for its environment and can change its spectral properties upon binding. (λexc 355 nm, λem 448 nm)
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 508 (1983).
    D 081 5 uM/ ~2.3mg, 5 x 5 uM CAS No.: [pending]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-dGMP )
       Fluorescent analogue of 2'- deoxyguanosine- 5’- monophosphate, useful for research into 5’-dGMP-dependent receptor proteins. (λexc 355 nm, λem 448 nm)
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 508 (1983).
    D 082 5 uM/ ~2.4mg, 5 x 5 uM CAS No.: [pending]

    2'- Deoxyadenosine- 5'- O- monophosphorothioate ( 5'-dAMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with 2'- deoxyadenosine- 5'- monophosphate.
       Vossberg & Eckstein, J. Biol. Chem., 257, 6595 - 6599 (1982).
    D 003 5 uM/ ~1.7 mg, 5 x 5 uM CAS No.: [64145-26-2]

    2'- Deoxycytidine- 5'- O- monophosphorothioate ( 5'-dCMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with 2'- deoxycytidine- 5'- monophosphate.
       Cummins & Potter, Phosphorus Sulfur, 30, 589 - 592 (1987).
    D 059 5 uM/ ~1.6 mg, 5 x 5 uM CAS No.: [64145-27-3]

    2'- Deoxyguanosine- 5'- O- monophosphorothioate ( 5'-dGMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with 2'- deoxyguanosine- 5'- monophosphate.
       Vosberg et al., Biochemistry 16, 3633 - 3640 (1977); Olsen et al., Biochemistry 29, 9546 - 9551 (1990)
    D 056 5 uM/ ~1.8 mg, 5 x 5 uM CAS No.: [87358-26-7]

    2'- Deoxyinosine- 5'- O- monophosphorothioate ( 5'-dIMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with 2'- deoxyinosine- 5'- monophosphate.
       Buschle & Lingnau, PCT Int. Appl. (2004), 33 pp., WO 2004084937
    D 060 5 uM/ ~1.7 mg, 5 x 5 uM CAS No.: [771477-45-3]

    2'- Deoxyuridine- 5'- O- monophosphosphorothioate ( 5'-dUMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with 2'- deoxypyrimidine- 5'- monophosphates.
       Golos et al., Biol. Chem., 382, 1439 - 1445 (2001).
    D 057 5 uM/ ~1.6 mg, 5 x 5 uM CAS No.: [205379-91-5]

    1, N6- Ethenoadenosine- 5'- O- monophosphate ( ε-5'-AMP )
       Fluorescent analogue of adenosine- 5'- monophosphate; (λexc 300 nm, λem 415 nm)
       Latchezar et al., J. Pharmacol. Exp. Ther., 298, 623-633, (2001); Vandenbunner et al., Proc. Nat. Acad. Sci. USA, 73, 2696 - 2700 (1976).
    E 005 50 uM/ ~21 mg, 5 x 50 uM CAS No.: [103213-41-8]

    Guanosine- 5'- O- monophosphorothioate ( 5'-GMPS )
       Substrate, competitive inhibitor or regulator of enzymes that interact with guanosine- 5'- monophosphate. Can be linked to structures with SH-groups via
       a disulfide bond.
       Macosko et al., RNA 5, 1158 - 1166 (1999); Wu et al., Bioconjugate Chem., 12, 842 - 844 (2001).
    G 018 10 uM/ ~3.8 mg, 5 x 10 uM CAS No.: [76310-16-2]

    N6- Methyladenosine- 5'- O- monophosphate ( N6-5'-Me-AMP )
       Activator of glycogen phosphorylase b.
       Morange et al., Eur. J. Biochem., 65, 553 - 563 (1976).
    M 038 10 uM/ ~3.6 mg, 5 x 10 uM CAS No.: [81921-35-9]

    2'-/3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-AMP )
       Fluorescent metabolite of MANT-cAMP and probe for 5’-AMP-binding receptors. Analogue of adenosine- 5’- monophosphate, useful for research into 5’-AMP
       -dependent receptor proteins. (λexc 355 nm, λem 448 nm)
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 508 (1983).
    M 037 10 uM/ ~4.8 mg, 5 x 10 uM CAS No.: [85287-53-2]

    2'-, 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-GMP )
       Fluorescent metabolite of MANT-cGMP and probe for 5’-GMP-binding receptors. Analogue of guanosine- 5’- monophosphate, useful for research into
       5’-GMP-dependent receptor proteins. (λexc 355 nm, λem 448 nm)
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983).
    M 042 10 uM/ ~5 mg, 5 x 10 uM CAS No.: [85287-54-3]

    2- Methylthioadenosine- 5'- O- monophosphate ( 2-MeS-5'-AMP )
       Potent adenylate cyclase-coupled platelet ADP P2Y purinoceptor antagonist.
       Brammer & Maguire, Brit. J. Pharmacol., 82, 61 - 72 (1984); Swennen et al., Biochem. Biophys. Res. Commun., 348, 1194 - 1199 (2006).
    M 031 10 uM/ ~3.9 mg, 5 x 10 uM CAS No.: [22140-20-1]

    Purine riboside- 5'- O- monophosphate ( 5'-PuMP )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with adenosine- 5'- monophosphate.
       Kozlowska et al., Toxicol. Lett., 104, 171 - 181 (1999).
    P 011 5 uM/ ~1.6 mg, 5 x 5 uM CAS No.: [13484-60-1]

    Thymidine- 5'- O- monophosphorothioate ( 5'-TMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with thymidine- 5'- monophosphate.
       Golos et al., Biol. Chem., 382, 1439 - 1445 (2001).
    T 004 5 uM/ ~1.6 mg, 5 x 5 uM CAS No.: [15548-51-3]

    Uridine- 5'- O- monophosphorothioate ( 5'-UMPS )
       Potential substrate, competitive inhibitor or regulator of enzymes that interact with uridine- 5'- monophosphate.
       Eckstein and Sternbach, Biochim. Biophys. Acta, 146, 618 - 619 (1967).
    U 006 5 uM/ ~1.7 mg, 5 x 5 uM CAS No.: [15548-52-4]