Fluorescent Nucleotides

  • 2- Aminopurine riboside- 3', 5'- monophosphate ( 2-NH2-cPuMP )
  • 2- Aminopurine riboside- 5'- O- triphosphate ( 2-NH2-PuTP )
  • 2- Aza- 1, N6- ethenoadenosine ( 2-Aza-ε-Ado )
  • 2- Aza- 1, N6- ethenoadenosine- 3', 5'- cyclic monophosphate ( 2-Aza-ε-cAMP )
  • 8- Azido- 1, N6- ethenoadenosine- 3', 5'- cyclic monophosphate ( 8-N3-ε-cAMP )
  • 8- Azido- N6- (2- [DY-547]- aminoethyl)adenosine- 3', 5'- cyclic monophosphate ( 8-N3-6-[DY-547]-AE-cAMP )
  • 6, 7- Bis(carboxymethoxy)coumarin- 4- yl)methyl- adenosine- 3', 5'- cyclic monophosphate ( BCMCM-caged cAMP )
  • [6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- 8- bromoadenosine- 3', 5'- cyclic monophosphate ( BCMCM-caged 8-Br-cAMP )
  • [6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( BCMCM-caged 8-Br-cGMP )
  • [6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- guanosine- 3', 5'- cyclic monophosphate ( BCMCM-caged cGMP )
  • 2'- Deoxy- 1, N6- ethenoadenosine ( ε-dAdo )
  • 2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- monophosphate ( ε-5'-dAMP )
  • 2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- triphosphate ( ε-dATP )
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- diphosphate ( MANT-dADP )
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-dAMP)
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-dATP )
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- diphosphate ( MANT-dGDP )
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-dGMP )
  • 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-dGTP
  • 2'-, 2''- O- ( Di- N'- methylanthraniloyl)- cyclic diguanosine monophosphate ( Di-MANT-c-diGMP )
  • 8- (2- [ DY-547]- aminoethylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate ( 8-[DY-547]-AET-2'-O-Me-cAMP )
  • 8- (2- [ DY-547]- aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[DY-547]-AET-cGMP )
  • 8- (2- [ DY-647]- aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[DY-647]-AET-cGMP )
  • 1, N6- Ethenoadenosine- 3', 5'- cyclic monophosphate ( ε-cAMP )
  • 1, N6- Ethenoadenosine- 5'- O- diphosphoribose ( ε-ADPR / ε-ADP-ribose )
  • 1, N6- Ethenoadenosine- 5'- O- monophosphate ( ε-5'-AMP )
  • 1, N6- Ethenoadenosine- 5'- O- triphosphate ( ε-ATP )
  • 8- (2- [ Fluoresceinyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate ( 8-Fluo-cAMP )
  • 8- (2- [ Fluoresceinyl]aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-Fluo-cGMP )
  • 2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cAMP )
  • 2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cGMP )
  • 2'- O- (N- Methylanthraniloyl)adenosine- 3', 5'- cyclic monophosphate ( MANT-cAMP )
  • 2'-/3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- diphosphate ( MANT-ADP )
  • 2'-/3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-AMP )
  • 2'-/3'- O- (N- Methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-ATP )
  • 2'- O- (N- Methylanthraniloyl)guanosine- 3', 5'- cyclic monophosphate ( MANT-cGMP )
  • 2'-/3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- diphosphate ( MANT-GDP )
  • 2'-, 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-GMP )
  • 2'-/3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-GTP )
  • 2'- / 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- [(β, γ)- imido]triphosphate ( MANT-GppNHp )
  • 8- (4- [N- Methylanthraniloyl]aminobutylamino)adenosine- 3', 5'- cyclic monophosphate ( 8-MABA-cAMP )
  • N6- (6- [N- Methylanthraniloyl]hexylamino)adenosine-3', 5'- cyclic monophosphate ( 6-MAH-cAMP )
  • 8- (2- [7- Nitro- 4- benzofurazanyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate ( 8-NBD-cAMP )
  • 8- (2- [7- Nitro- 4- benzofurazanyl]aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-NBD-cGMP )
  • 8- [ Pharos-450]- adenosine- 3', 5'- cyclic monophosphate ( 8-[φ-450]-cAMP )
  • 8- [ Pharos-450]- guanosine- 3', 5'- cyclic monophosphate ( 8-[φ-450]-cGMP )
  • 8- [ Pharos-575]- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate ( 8-[φ-575]-2'-O-Me-cAMP )
  • 8- [ Pharos-575]- adenosine- 3', 5'- cyclic monophosphate ( 8-[φ-575]-cAMP )
  • 8- [ Pharos-575]- guanosine- 3', 5'- cyclic monophosphate ( 8-[φ-575]-cGMP )
     

  • 2- Aminopurine riboside- 3', 5'- monophosphate ( 2-NH2-cPuMP )
       Fluorescent cyclic nucleotide.
       Scheit, J. Carbohydr. Nucleosides, Nucleotides, 1, 385 - 399 (1974).
    A 027 5 uM/~1.8mg, 5 x 5 uM λexc 305 nm, λem 370 nm. CAS No.: [42467-66-3]

    2- Aminopurine riboside- 5'- O- triphosphate ( 2-NH2-PuTP )
       Fluorescent triphosphate analogue.
       McClure & Scheit, FEBS Lett., 32, 267 - 269 (1973).
    A 124 5 uM/~2.5 mg, 5 x 5 uM λexc 305 nm, λem 370 nm. CAS No.: [23001-60-7]

    2- Aza- 1, N6- ethenoadenosine ( 2-Aza-ε-Ado )
       Fluorescent analogue of adenosine.
       Tsou et al., Nucl. Acids Res., 1, 531 - 547 (1974); Yip & Tsou, Tetrahedron Lett., 33, 3087 - 3090 (1973).
    A 086 10 uM/~2.9mg, 5 x 10 uM λexc 358 nm, λem 494 nm. at pH 5 CAS No.: [50663-82-6]

    2- Aza- 1, N6- ethenoadenosine- 3', 5'- cyclic monophosphate ( 2-Aza-ε-cAMP )
       Fluorescent cAMP analogue
       Tsou et al., Anal. Biochem., 60, 163 - 169 (1974); Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
    A 015 5 uM/~1.9mg, 5 x 5 uM λexc 358 nm, λem 494 nm. CAS No.: [50663-90-6]

    8- Azido- 1, N6- ethenoadenosine- 3', 5'- cyclic monophosphate ( 8-N3-ε-cAMP )
       Nonfluorescent cAMP analogue, that can be used for labelling of cAMP receptors.
       Keeler & Campbell, Biochem. Biophys. Res. Commun., 72, 575 - 80 (1976); Dreyfuss et al., Proc. Nat. Acad. Sci. USA, 75, 1199 - 1203 (1978).
    A 077 1 uM/~0.4 mg, 5 x 1 uM λmax 237, 289 & 313 nm CAS No.: [60902-12-7]

    8- Azido- N6- (2- [DY-547]- aminoethyl)adenosine- 3', 5'- cyclic monophosphate ( 8-N3-6-[DY-547]-AE-cAMP )
       8-N3-6-[DY547]-AE-cAMP is a light sensitive analogue for photoaffinity labelling. It can be immobilized within a cyclic AMP binding site by illumination with
       UV light.
    A 100 0.1 uM/~0.1 mg, 5 x 0.1 uM λexc 557 nm, λem 574 nm. CAS No.: [pending]

    6, 7- Bis(carboxymethoxy)coumarin- 4- yl)methyl- adenosine- 3', 5'- cyclic monophosphate
       ( BCMCM-caged cAMP )
       Caged cyclic AMP, releasing a fluorescent coumarin upon uncaging.
       Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).
    B 016 0.1 uM/~68 ug, 5 x 0.1 uM   CAS No.: [339291-51-9]

    6, 7- Bis(carboxymethoxy)coumarin- 4- yl)methyl- adenosine- 3', 5'- cyclic monophosphate
       ( BCMCM-caged cAMP )
       Caged cyclic AMP, releasing a fluorescent coumarin upon uncaging.
       Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).
    B 018 0.1 uM/~76 ug, 5 x 0.1 uM λmax 346 nm  CAS No.: [370091-64-8]

    [6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- 8- bromoguanosine- 3', 5'- cyclic monophosphate
       ( BCMCM-caged 8-Br-cGMP )
       Caged cyclic GMP, releasing a fluorescent coumarin upon un-caging.
       Hagen et al., Angew. Chem. Int. Ed., 40, 1046 - 1048 (2001).
    B 019 0.1 uM/~78 ug, 5 x 0.1 uM λmax 346 nm  CAS No.: [370091-68-2]

    [6, 7- Bis(carboxymethoxy)coumarin- 4- yl]methyl- guanosine- 3', 5'- cyclic monophosphate
       ( BCMCM-caged cGMP )
       Caged cyclic GMP, releasing a fluorescent coumarin upon uncaging.
    B 017 0.1 uM/~69 ug, 5 x 0.1 uM λmax 347 nm CAS No.: [339291-52-0]

    2'- Deoxy- 1, N6- ethenoadenosine ( ε-dAdo )
       Fluorescent analogue of 2'-deoxyadenosine.
    D 080 5 uM/~1.4 mg, 5 x 5 uM λexc 300 nm, λem 410 nm. CAS No.: [68498-25-9]

    2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- monophosphate ( ε-5'-dAMP )
       Fluorescent analogue of 2'-deoxy-5'-AMP.
    D 077 5 uM/~1.8 mg, 5 x 5 uM λexc 300 nm, λem 415 nm. CAS No.: [60508-81-8]

    2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- triphosphate ( ε-dATP )
       Fluorescent analogue of dATP .
    D 078 5 uM/~2.6 mg, 5 x 5 uM λexc 300 nm, λem 415 nm. CAS No.: [81004-54-8]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- diphosphate ( MANT-dADP )
       Fluorescent analogue of 2'- deoxyadenosine- 5’- diphosphate, useful for research into 5’-dADP-dependent receptor proteins.
    D 083 5 uM/~2.7 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [91828-83-0]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-dAMP)
       Fluorescent analogue of 2'- deoxyadenosine- 5’- monophosphate, useful for research into 5’-dAMP-dependent receptor proteins.
    D 081 5 uM/~2.3 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [pending]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-dATP )
       Fluorescent analogue of 2'- deoxyadenosine- 5’- triphosphate, useful for research into dATP-dependent receptor proteins.
    D 085 5 uM/~3.1 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [128113-53-1]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- diphosphate ( MANT-dGDP )
       Fluorescent analogue of 2'- deoxyguanosine- 5’- diphosphate, useful for research into 5’-dGDP-dependent receptor proteins.
    D 084 5 uM/~2.8 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [127383-33-9]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-dGMP )
       Fluorescent analogue of 2'- deoxyguanosine- 5’- monophosphate, useful for research into 5’-dGMP-dependent receptor proteins.
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 508 (1983)
    D 082 5 uM/~2.4 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [pending]

    2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-dGTP )
       Fluorescent analogue of 2'- deoxyguanosine- 5’- triphosphate, useful for research into 5’-dGTP-dependent receptor proteins.
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 508 (1983)
    D 086 5 uM/~3.2 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [124615-99-2]

    2'-, 2''- O- ( Di- N'- methylanthraniloyl)- cyclic diguanosine monophosphate ( Di-MANT-c-diGMP )
       Fluorescent analogue of the bacterial second messenger c-diGMP.
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 508 (1983)
    D 101 0.1 uM/~0.1 mg, 5 x 0.1 uM λexc 355 nm, λem 448 nm. CAS No.: [pending]

    8- (2- [ DY-547]- aminoethylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate
       ( 8-[DY-547]-AET-2'-O-Me-cAMP )
       Fluorescent activator of the exchange protein directly activated by cyclic AMP (Epac) or cAMP-GEF, respectively, does not activate PKA
       Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
    D 089 0.1 uM/~0.1 mg, 5 x 0.1 uM λexc 557 nm, λem 574 nm. CAS No.: [pending]

    8- (2- [ DY-547]- aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[DY-547]-AET-cGMP )
       Fluorescent cGMP analogue e.g. for research focussed on kinetic studies of CNG ion channels and other cGMP-reponsive binding proteins
       Biskup et al., Nature, 446, 440 - 443 (2007).
    D 087 0.1 uM/~0.1 mg, 5 x 0.1 uM λexc 557 nm, λem 574 nm. CAS No.: [pending]

    8- (2- [ DY-647]- aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[DY-647]-AET-cGMP )
       Fluorescent cGMP analogue e.g. for research focussed on kinetic studies of CNG ion channels and other cGMP-reponsive binding proteins
    D 090 0.1 uM/~0.1 mg, 5 x 0.1 uM λexc 649 nm, λem 666 nm. CAS No.: [pending]

    1, N6- Ethenoadenosine- 3', 5'- cyclic monophosphate ( ε-cAMP )
       Fluorescent analogue of cyclic AMP
       Secrist et al., Biochemistry, 11, 3499 - 3506 (1972).
    E 001 10 uM/~3.8 mg, 5 x 10 uM λexc 300 nm, λem 415 nm. CAS No.: [103213-51-0]

    1, N6- Ethenoadenosine- 5'- O- diphosphoribose ( ε-ADPR / ε-ADP-ribose )
       Fluorescent analogue of ADP-ribose that can be used in fluorometric assays.
       Bobalova et al., Anal. Biochem., 305, 269 - 276 (2002); Song et al., J. Biochem. Biophys. Methods, 63, 161 - 169 (2005).
    E 013 10 uM/~5.8 mg, 5 x 10 uM λexc 300 nm, λem 410 nm. CAS No.: [69699-76-9]

    1, N6- Ethenoadenosine- 5'- O- monophosphate ( ε-5'-AMP )
       Fluorescent analogue of adenosine- 5'- monophosphate
       Latchezar et al., J. Pharmacol. Exp. Ther., 298, 623-633, (2001); Vandenbunner et al., Proc. Nat. Acad. Sci. USA, 73, 2696 - 2700 (1976).
    E 005 50 uM/~21 mg, 5 x 50 uM λexc 300 nm, λem 415 nm. CAS No.: [103213-41-8]

    1, N6- Ethenoadenosine- 5'- O- triphosphate ( ε-ATP )
       Fluorescent ATP analogue
       Yip et al., Tetrahedron Lett., 33, 3087 - 3090 (1973).
    E 004 5 uM/~2.7 mg, 5 x 5 uM λexc 300 nm, λem 415 nm. CAS No.: [60777-99-3]

    8- (2- [ Fluoresceinyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate ( 8-Fluo-cAMP )
       cyclic AMP conjugated with fluorescein
       Schwede et al., Biochemistry, 39, 8803 - 8812 (2000).
    F 002 1 uM/~0.8 mg, 5 x 1 uM λexc 494 nm, λem 517 nm. CAS No.: [293296-57-8]

    8- (2- [ Fluoresceinyl]aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-Fluo-cGMP )
       Fluorescent cyclic GMP analogue
       Tanaka et al, Biochemistry 28, 2776 - 2784 (1989); Koutalos et al., Biophys. J., 69, 2163 - 2167 (1995).
    F 001 1 uM/~0.8 mg, 5 x 1 uM λexc 494 nm, λem 517 nm. CAS No.: [pending]

    2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cAMP )
       Fluorescent, PKA-inactive cyclic AMP analogue
       Huang et al., J. Biomol. Screen., 7, 215 - 222 (2002).
    F 003 1 uM/~0.9 mg, 5 x 1 uM λexc 494 nm, λem 517 nm. CAS No.: [pending]

    2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-Fluo-AHC-cGMP )
       Fluorescent, PKG-inactive cyclic GMP analogue
       Huang et al., J. Biomol. Screen., 7, 215 - 222 (2002).
    F 004 1 uM/~0.9 mg, 5 x 1 uM λexc 494 nm, λem 517 nm. CAS No.: [pending]

    2'- O- (N- Methylanthraniloyl)adenosine- 3', 5'- cyclic monophosphate ( MANT-cAMP )
       Fluorescent cyclic AMP analogue, suitable for phosphodiesterase studies.
       Hiratsuka, J. Biol. Chem., 257, 13354 - 13358 (1982); Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
    M 008 10 uM/~4.8 mg, 5 x 10 uM λexc 350 nm, λem 445 nm. CAS No.: [83707-14-6]

    2'-/3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- diphosphate ( MANT-ADP )
       Fluorescent analogue of adenosine- 5’- diphosphate, useful for research into ADP-dependent receptor proteins.
       Cheng et al., Biochemistry, 37, 5288 - 5295 (1998).
    M 040 5 uM/~2.8 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [151481-85-5]

    2'-/3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- monophosphate ( MANT-5'-AMP )
       Fluorescent analogue of 5'-AMP, useful for research into 5’-AMP-dependent receptor proteins.
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 508 (1983).
    M 037 10 uM/~4.8 mg, 5 x 10 uM λexc 355 nm, λem 448 nm. CAS No.: [85287-53-2]

    2'-/3'- O- (N- Methylanthraniloyl)adenosine- 5'- O- triphosphate ( MANT-ATP )
       Fluorescent analogue of ATP, useful for research into ATP-dependent receptor proteins.
       Mocz et al., Biochemistry, 37, 9862 - 9869 (1998); Woodward et al., Biochemistry, 30, 422 - 430 (1991). Potent inhibitor of adenylate cyclase (Mou et al., J. Biol. Chem.,
       280, 7253 - 7261 (2001)).
    M 030 5 uM/~3.2 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [151481-86-6]

    2'- O- (N- Methylanthraniloyl)guanosine- 3', 5'- cyclic monophosphate ( MANT-cGMP )
       Fluorescent, PKG-inactive cyclic GMP analogue, suitable for phosphodiesterase studies.
       Hiratsuka, J. Biol. Chem., 257, 13354 - 13358 (1982); Johnson, Anal. Biochem., 162, 291 - 295 (1987); Brown et al., Biochem. Biophys. Res. Commun., 224, 684 - 689 (1996).
    M 009 10 uM/~5 mg, 5 x 10 uM λexc 350 nm, λem 441 nm. CAS No.: [83707-15-7]

    2'-/3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- diphosphate ( MANT-GDP )
       Fluorescent analogue of guanosine- 5’- diphosphate, useful for research into GDP-dependent receptor proteins.
       Wieden et al., J. Biol. Chem., 277, 6032 - 6036 (2002).   Rehmann, Methods Enzymol., 407, 159 - 173 (2006).
    M 041 5 uM/~2.9 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [148821-02-7]

    2'-, 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- monophosphate ( MANT-5'-GMP )
       Fluorescent analogue of 5'-GMP, useful for research into 5’-GMP-dependent receptor proteins.
       Hiratsuka, Biochim. Biophys. Acta, 742, 496 - 503 (1983).
    M 042 10 uM/~5 mg, 5 x 10 uM λexc 355 nm, λem 448 nm. CAS No.: [85287-54-3]

    2'-/3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- triphosphate ( MANT-GTP )
       Fluorescent analogue of guanosine- 5’- triphosphate ,useful for research into GTP-dependent receptor proteins.
       Gille & Seifert, J. Biol. Chem., 278, 12672 - 12679 (2003).
    M 032 5 uM/~3.3 mg, 5 x 5 uM λexc 355 nm, λem 448 nm. CAS No.: [148821-03-8]

    2'- / 3'- O- (N'- Methylanthraniloyl)guanosine- 5'- O- [(β, γ)- imido]triphosphate ( MANT-GppNHp )
       Fluorescent form of the hydrolysis-resistant GppNHp, useful for research into GTP- dependent receptor proteins.
       Herrmann et al., J. Biol. Chem., 270, 2901 - 2905 (1994); Gille. & Seifert, J. Biol. Chem., 278, 12672 - 12679 (2003); Zhang et al., J. Biol. Chem. 280, 33200 - 33205 (2005).
    M 047 1 uM/~0.7 mg, 5 x 1 uM λexc 355 nm, λem 448 nm. CAS No.: [148821-01-6]

    8- (4- [N- Methylanthraniloyl]aminobutylamino)adenosine- 3', 5'- cyclic monophosphate ( 8-MABA-cAMP )
       Fluorescent, membrane- permeant cyclic AMP analogue.
       Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
    M 016 5 uM/~2.9 mg, 5 x 5 uM λexc 261 nm, λem 278 nm. CAS No.: [342029-95-2]

    N6- (6- [N- Methylanthraniloyl]hexylamino)adenosine-3', 5'- cyclic monophosphate ( 6-MAH-cAMP )
       Fluorescent, membrane- permeant cyclic AMP analogue.
       Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001); Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006).
       For modifications with the methylanthraniloyl group please compare: Theyssen, J. Mol. Biol., 263, 657 - 670 (1996).
    M 017 5 uM/~2.9 mg, 5 x 5 uM λexc 333 nm, λem 437 nm. CAS No.: [723313-27-7]

    8- (2- [7- Nitro- 4- benzofurazanyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate ( 8-NBD-cAMP )
       Potent membrane-permeant fluorescent activator of cAMP-dependent protein kinase.
       Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
    N 002 1 uM/~0.6 mg, 5 x 1 uM λexc 471 nm, λem 536 nm. CAS No.: [221905-51-7]

    8- (2- [7- Nitro- 4- benzofurazanyl]aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-NBD-cGMP )
       Potent membrane-permeant fluorescent activator of both isozymes I a and I ß of cGMP-dependent protein kinase.
       Ruf et al. in Heilmeyer (ed.), Signal Transduction and Protein Phosphorylation, Ser. A, Life Sci., 135, 99 - 104 ( 1987) Plenum Press, NATO ASI.
    N 001 1 uM/~0.7 mg, 5 x 1 uM λexc 475 nm, λem 525 nm. CAS No.: [115993-88-9]

    8- [ Pharos-450]- adenosine- 3', 5'- cyclic monophosphate ( 8-[φ-450]-cAMP )
       The fluorophore can be excited e.g. by a He/Cd laser. Due to its high lipophilicity and bright green fluorescence 8-[φ-450]-cAMP is especially suitable
       for studies with intact cells.
    P 024 1 uM/~72 ug , 5 x 1 uM λexc 450 nm, λem 534 nm. CAS No.: [pending]

    8- [ Pharos-450]- guanosine- 3', 5'- cyclic monophosphate ( 8-[φ-450]-cGMP )
       The fluorophore can be excited e.g. by a He/Cd laser. Due to its high lipophilicity and bright green fluorescence 8-[φ-450]-cAMP is especially suitable
       for studies with intact cells.
    P 025 1 uM/~74 ug , 5 x 1 uM λexc 450 nm, λem 534 nm. CAS No.: [pending]

    8- [ Pharos-575]- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate ( 8-[φ-575]-2'-O-Me-cAMP )
       Fluorescent Epac agonist. The fluorophore can be excited e.g. by a Kr/Ar laser. Due to its high lipophilicity and bright red fluorescence 8-[φ-575]-cAMP is
       especially suitable for studies with intact cells.
       Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
    P 021 1 uM/~74 ug , 5 x 1 uM λexc 577 nm, λem 605 nm. CAS No.: [pending]

    8- [ Pharos-575]- adenosine- 3', 5'- cyclic monophosphate ( 8-[φ-575]
       Membrane-permeant, fluorescent analogue of cyclic AMP. The fluorophore can be excited e.g. by a Kr/Ar laser. Due to its high lipophilicity and bright red
       fluorescence 8-[φ-575]-cAMP is especially suitable for studies with intact cells.
       Moll et al., BMC Biochem., 9, 18 (2008).
    P 019 0.1 uM/~72 ug , 5 x 0.1 uM λexc 577 nm, λem 605 nm. CAS No.: [pending]

    8- [ Pharos-575]- guanosine- 3', 5'- cyclic monophosphate ( 8-[φ-575]-cGMP )
       Membrane permeant fluorescent analogue of cyclic GMP. The fluorophore can be excited e.g. by a Kr/Ar laser. Due to its high lipophilicity and bright red
       fluorescence 8-[φ-575]-cGMP is especially suitable for studies with intact cells.
    P 020 0.1 uM/~74 ug , 5 x 0.1 uM λexc 575 nm, λem 605 nm. CAS No.: [pending]