cNMP with Pyrimidine Nucleobase

  • Cytidine- 3', 5'- cyclic monophosphate ( cCMP )Cat. No.: C 001
  • Cytidine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( cCMP-AM )Cat. No.: C 067
  • Cytidine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-cCMPS )Cat. No.: C 065
  • Cytidine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-cCMPS )Cat. No.: C 066
  • N4, 2'- O- Dibutyrylcytidine- 3', 5'- cyclic monophosphate ( DB-cCMP )Cat. No.: D 075
  • 2'- O- (N'- Methylanthraniloyl)cytidine- 3', 5'- cyclic monophosphate ( MANT-cCMP )Cat. No.: M 053
  • Thymidine- 3', 5'- cyclic monophosphate ( cTMP )Cat. No.: T 005
  • Uridine- 2', 3'- cyclic monophosphate ( 2',3'-cUMP )Cat. No.: U 004
  • Uridine- 3', 5'- cyclic monophosphate ( cUMP )Cat. No.: U 001
     

  • Cytidine- 3', 5'- cyclic monophosphate ( cCMP )
       For other salt forms, more PDE-resistant and membrane-permeant analogues please inquire. Potential further second messenger.
       Newton, Nucleosides & Nucleotides 14, 743 - 747 (1995).
    C 001 50 uM/~16 mg, 5 x 50 uM CAS No.: [54925-33-6]

    Cytidine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( cCMP-AM )
       Membrane-permeant, metabolically activatable prodrug form of the potential further second messenger cyclic CMP.
    C 067 1 uM/~0.4 mg, 5 x 1 uM CAS No.: [pending]

    Cytidine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-cCMPS )
       Sulfur-modified form of the potential second messenger cyclic CMP and potential PDE-resistant inhibitor of cCMP-binding proteins.
    C 065 1 uM/~0.3 mg, 5 x 1 uM CAS No.: [87063-79-4]

    Cytidine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-cCMPS )
       Sulfur-modified form of the potential second messenger cyclic CMP and potential PDE-resistant activator of cCMP-binding proteins.
       Eckstein & Kutzke, Tetrahedr. Lett., 27, 1657 -1660 (1986).
    C 066 5 uM/~1.7 mg, 5 x 5 uM CAS No.: [87063-81-8]

    N4, 2'- O- Dibutyrylcytidine- 3', 5'- cyclic monophosphate ( DB-cCMP )
       Membrane-permeant, metabolically activatable prodrug form of the potential further second messenger cyclic CMP.
       Yanagida et al., Neurosci. Lett., 114, 323 - 328 (1990).
    D 075 10 uM/~4.7 mg, 5 x 10 uM CAS No.: [64649-87-2]

    2'- O- (N'- Methylanthraniloyl)cytidine- 3', 5'- cyclic monophosphate ( MANT-cCMP )
       Fluorescent, membrane-permeant cyclic CMP analogue, potentially suitable for phosphodiesterase studies. The compound is expected to show a decrease in fluorescence when cleaved by PDE.
       Hiratsuka, J. Biol. Chem., 257, 13354 - 13358 (1982).
    M 053 5 uM/~2.3 mg, 5 x 5 uM CAS No.: [pending]

    Thymidine- 3', 5'- cyclic monophosphate ( cTMP )
       Cyclic nucleotide analogue for receptor mapping studies.
       Riegel et al., J. Exp. Biol., 201, 3411 - 3418 (1998).
    T 005 5 uM/~1.6 mg, 5 x 5 uM CAS No.: [76567-90-3]

    Uridine- 2', 3'- cyclic monophosphate ( 2',3'-cUMP )
       C9H10N2O8P.Na; MW 328.2; λmax 260 nm; ε 10000; sodium salt, purity > 97% HPLC.
       Tomasz, Nucleic Acid Chem., 2, 875 - 879 (1978); Cheung & Abrash, Biochemistry, 3, 1883 ? 1889 (1964).
    U 004 50 uM/~16 mg, 5 x 50 uM CAS No.: [15718-50-0]

    Uridine- 3', 5'- cyclic monophosphate ( cUMP )
       C9H10N2O8P.Na; MW 328.2; λmax 262 nm; ε 10200; sodium salt, purity > 98% HPLC.
       Blecher et al., Arch. Biochem. Biophys., 142, 351 - 362 (1971); Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006).
    U 001 50 uM/~16 mg, 5 x 50 uM CAS No.: [15718-50-0]