cGMP Ligands for Immobilization

  • 2'- O- (2- Aminoethylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-AEC-cGMP )Cat. No.: A 075
  • 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-AET-cGMP )Cat. No.: A 029
  • N2- (6- Aminohexyl)guanosine- 3', 5'- cyclic monophosphate ( 2-AH-cGMP )Cat. No.: A 055
  • 2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-AHC-cGMP )Cat. No.: A 048
  • 2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-2'-AHC-cGMPS )Cat. No.: A 123
  • 2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-2'-AHC-cGMPS )Cat. No.: A 067
  • β- (4- Azidophenyl)- 1, N2- etheno- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( 4-N3-PET-8-Br-cGMP )Cat. No.: A 102
  • 2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-MS-cGMP )Cat. No.: M 015

     


  • 2'- O- (2- Aminoethylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-AEC-cGMP )
       Cyclic GMP analogue suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling structures
       including fluorophores .
       Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).
    A 075 5 uM/ ~2.2 mg, 5 x 5 uM CAS No.: [pending]

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-AET-cGMP )
       Suitable as a ligand in affinity chromatography (compare Cat. No. A 019) and for modification with fluorophores.
       Dills et al., Biochemistry, 15, 3724 - 3730 (1976).
    A 029 5 uM/ ~2.1 mg, 5 x 5 uM CAS No.: [115974-70-4]

    N2- (6- Aminohexyl)guanosine- 3', 5'- cyclic monophosphate ( 2-AH-cGMP )
       Suitable as ligand in affinity chromatography of cGMP-binding proteins (compare Cat. No. A 056) and for modification with fluorophores.
       Hebert et al., J. Biol. Chem., 273, 5557 - 5565 (1998)., Dills et al., Biochemistry, 15, 3724 - 3730 (1976).
    A 055 5 uM/ ~2.2 mg, 5 x 5 uM CAS No.: [205368-58-7]

    2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate ( 2'-AHC-cGMP )
       Cyclic GMP analogue suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling structures
       including fluorophores.
       Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).
    A 048 5 uM/ ~2.4 mg, 5 x 5 uM CAS No.: [pending]

    2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-2'-AHC-cGMPS )
       PDE-stable cyclic GMP analogue suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling
       structures including fluorophores.
       Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).
    A 123 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [pending]

    2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-2'-AHC-cGMPS )
       PDE-stable cyclic GMP analogue suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling
       structures including fluorophores.
       Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).
    A 067 5 uM/ ~2.5 mg, 5 x 5 uM CAS No.: [pending]

    β- (4- Azidophenyl)- 1, N2- etheno- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( 4-N3-PET-8-Br-cGMP )
       Analogue for photoaffinity labelling of cGMP-responsive receptors, considered to be a isozyme-selective activator of cGMP-dependent protein kinase I α
       and β.
    A 102 1 uM/ ~0.6 mg, 5 x 1 uM CAS No.: [pending]

    2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate ( 2'-O-MS-cGMP )
       Cyclic GMP analogue, suitable for coupling of various ligands including proteins for ELISA. For a structure with a hydrolytically and enzymatically much more
       stable linkage please compare 2'-AHC-cGMP (Cat. No. A 048).
    M 015 25 uM/ ~12 mg, 5 x 25 uM CAS No.: [39118-26-8]