Affinity Gels

  • N6- (2- Aminoethyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 6-AE-cAMP-Agarose )Cat. No.: A 111
  • N6- (2- Aminoethyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-6-AE-cAMPS-Agarose )Cat. No.: A 109
  • 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 8-AEA-cAMP-Agarose )Cat. No.: A 020
  • 2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 2-AEA-cAMP-Agarose )Cat. No.: A 110
  • 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose ( Rp-8-AEA-cAMPS-Agarose )Cat. No.: A 007
  • 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose ( Sp-8-AEA-cAMPS-Agarose )Cat. No.: A 008
  • 2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-2-AEA-cAMPS-Agarose )Cat. No.: A 087
  • 2'- O- (6- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 2'-AEC-cAMP-Agarose )Cat. No.: A 112
  • 2'- O- (6- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-2'-AHC-cAMPS-Agarose)
       Cat. No.: A 122
  • 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 8-AET-cGMP-Agarose )Cat. No.: A 019
  • 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose ( Rp-8-AET-cGMPS-Agarose )Cat. No.: A 009
  • 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose ( Sp-8-AET-cGMPS-Agarose )Cat. No.: A 010
  • N6- (6- Aminohexyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 6-AH-cAMP Agarose )Cat. No.: A 036
  • N6- (6- Aminohexyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-6-AH-cAMPS-Agarose )Cat. No.: A 108
  • N2- (6- Aminohexyl)guanosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2-AH-cGMP Agarose )Cat. No.: A 056
  • 8- (6- Aminohexylamino)- 2'- O- methyladenosine- 3', 5'- cylic monophosphate, immobilized on agarose ( 8-AHA-2'-O-Me-cAMP-Agarose )Cat. No.: A 057
  • 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2-AHA-cAMP-Agarose )Cat. No.: A 054
  • 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 8-AHA-cAMP Agarose )Cat. No.: A 028
  • 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose ( Rp-8-AHA-cAMPS-Agarose )Cat. No.: A 012
  • 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-8-AHA-cAMPS-Agarose )Cat. No.: A 013
  • 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized to agarose gel ( Sp-2-AHA-cAMPS-Agarose )Cat. No.: A 069
  • 2'- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2'-AHC-cAMP-Agarose )Cat. No.: A 058
  • 2'- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-2'-AHC-cAMPS-Agarose )
       Cat. No.: A 050
  • 2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2'-AHC-cGMP-Agarose )Cat. No.: A 059
  • 2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose gel ( Rp-2'-AHC-cGMPS-Agarose )
       Cat. No.: A 051
  • 2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-2'-AHC-cGMPS-Agarose )
       Cat. No.: A 052

     


  • N6- (2- Aminoethyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 6-AE-cAMP-Agarose )
       cyclic AMP immobilized on agarose by an aminoethyl spacer attached to position 6 of the ligand. The gel can be used for affinity chromatography of various
       cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Murashima et al., Biochemistry, 29, 5285 - 5292 (1990).
    A 111 0.6 ml, 2.5 ml, 6 ml  

    N6- (2- Aminoethyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel
       ( Sp-6-AE-cAMPS-Agarose )
       PDE-resistant Sp-cAMPS immobilized on agarose by an aminoethyl spacer attached to position 6 of the ligand. Free Sp-cAMPS is only very slowly
       metabolized by corresponding phosphodiesterases and thus represents an extraordinary stable ligand.
    A 109 0.6 ml, 2.5 ml, 6 ml  

    8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 8-AEA-cAMP-Agarose )
       cyclic AMP immobilized on agarose by an aminoethylamino spacer attached to position 8 of the ligand. The gel can be used for affinity chromatography of
       various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Dills et al., Biochemistry, 15, 3724 - 3730 (1976); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
    A 111 0.6 ml, 2.5 ml, 6 ml  

    2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 2-AEA-cAMP-Agarose )
       cyclic AMP immobilized on agarose by an aminoethylamino spacer attached to position 2 of the ligand. The gel can be used for affinity chromatography of
       various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
    A 110 0.6 ml, 2.5 ml, 6 ml  

    8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose
       ( Rp-8-AEA-cAMPS-Agarose )
       The metabolically stable protein kinase A inhibitor Rp-cAMPS (Cat. No. A 002) immobilized on agarose by an aminoethylamino spacer attached to position 8
       of the ligand. Free Rp-cAMPS binds to the protein kinase A holoenzyme, but prevents dissociation to free catalytic and regulatory subunits.
    A 007 0.6 ml, 2.5 ml, 6 ml  

    8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose
       ( Sp-8-AEA-cAMPS-Agarose )
       The protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer attached to position 8 of the ligand. Free Sp-cAMPS is only
       very slowly metabolized by corresponding phosphodiesterases and thus represents an extraordinary stable ligand.
       Dills, W.L.; Biochem. Biophys. Res. Commun., 62, 70 - 77 (1975)
    A 008 0.6 ml, 2.5 ml, 6 ml  

    2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel
       ( Sp-2-AEA-cAMPS-Agarose )
       The protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer attached to position 2 of the ligand. Free Sp-cAMPS is only
       very slowly metabolized by corresponding phosphodiesterases and thus represents an extraordinary stable ligand. The gel can be used for affinity
       chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
    A 087 0.6 ml, 2.5 ml, 6 ml  

    2'- O- (6- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel
       ( 2'-AEC-cAMP-Agarose )
       The protein kinase A activator cyclic AMP immobilized on agarose by an aminoethylcarbamoyl spacer attached to the ribose 2' position of the ligand. The gel
       can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'- ribose hydroxyl
       group such as some phosphodiesterases.
    A 112 0.6 ml, 2.5 ml, 6 ml  

    2'- O- (6- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel
       ( Sp-2'-AHC-cAMPS-Agarose )
       The protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer attached to the ribose 2' position of the ligand. The gel
       can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'- ribose hydroxyl
       group such as some phosphodiesterases.
    A 122 0.6 ml, 2.5 ml, 6 ml  

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 8-AET-cGMP-Agarose )
       cyclic GMP immobilized on agarose by an aminoethylthio spacer attached to position 8 of the ligand (8-AET-cGMP). The gel can be used for affinity
       chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Schlossmann et al., Nature, 404, 197 - 201 (2000); Kim & Park, J. Biochem. Mol. Biol., 36, 299 - 304 (2003); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
    A 019 0.6 ml, 2.5 ml, 6 ml  

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose
       ( Rp-8-AET-cGMPS-Agarose )
       The metabolically stable protein kinase G inhibitor Rp-cGMPS immobilized on agarose by an aminoethylthio spacer attached to position 8 of the ligand. The
       gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
    A 009 0.6 ml, 2.5 ml, 6 ml  

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose
       ( Sp-8-AET-cGMPS-Agarose )
       The protein kinase G activator Sp-cGMPS (Cat. No. G 017) immobilized on agarose by an aminoethylthio spacer attached to position 8 of the ligand. The gel
       can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
    A 010 0.6 ml, 2.5 ml, 6 ml  

    N6- (6- Aminohexyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 6-AH-cAMP Agarose )
       Cyclic AMP immobilized on agarose by an aminohexyl spacer attached to position 6 of the ligand (6-AH-cAMP). The gel can be used for affinity
       chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Poteet-Smith et al., J. Biol. Chem., 272, 379 - 388 (1997).
    A 036 0.6 ml, 2.5 ml, 6 ml  

    N6- (6- Aminohexyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel
       ( Sp-6-AH-cAMPS-Agarose )
       Sp-cAMPS immobilized on agarose by an aminohexyl spacer attached to position 6 of the ligand (Sp-6-AH-cAMPS). The gel can be used for affinity
       chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
    A 108 0.6 ml, 2.5 ml, 6 ml  

    N2- (6- Aminohexyl)guanosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2-AH-cGMP Agarose )
       Cyclic GMP immobilized on agarose by an aminohexyl spacer attached to the 2- amino group of the ligand. The gel can be used for affinity chromatography of
       various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Kim & Park, J. Biochem. Mol. Biol., 36, 299 - 304 (2003).
    A 056 0.6 ml, 2.5 ml, 6 ml  

    8- (6- Aminohexylamino)- 2'- O- methyladenosine- 3', 5'- cylic monophosphate, immobilized on agarose
       ( 8-AHA-2'-O-Me-cAMP-Agarose )
       cAMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer attached to position 8 of the ligand. Considered to
       be suitable for affinity chromatography of various cAMP-responsive proteins, especially those which tolerate modification of the ribose 2'-hydroxy group, such
       as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases.
       Borland et al., Mol. Pharmacol., 69, 374 - 384 (2006).
    A 057 0.6 ml, 2.5 ml, 6 ml  

    2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2-AHA-cAMP-Agarose )
       Cyclic AMP immobilized on agarose by an aminohexylamino spacer attached to position 2 of the ligand. The gel can be used for affinity chromatography of
       various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Iwitzki, F., PhD Thesis, University of Bremen, Germany, 1993; Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
    A 054 0.6 ml, 2.5 ml, 6 ml  

    8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel ( 8-AHA-cAMP Agarose )
       Cyclic AMP immobilized on agarose by an aminohexylamino spacer attached to position 8 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
       Dills et al., Biochemistry, 15, 3724 - 3730 (1976).
    A 028 0.6 ml, 2.5 ml, 6 ml  

    8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose
       ( Rp-8-AHA-cAMPS-Agarose )
       The metabolically stable protein kinase A inhibitor Rp-cAMPS (Cat. No. A 002) immobilized on agarose by an aminohexylamino spacer attached to position 8
       of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinase A (presumably as its
       holoenzyme), phosphodiesterases and others.
    A 012 0.6 ml, 2.5 ml, 6 ml  

    8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel
       ( Sp-8-AHA-cAMPS-Agarose )
       The protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer attached to position 8 of the ligand. The gel can be used for
       affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
    A 013 0.6 ml, 2.5 ml, 6 ml  

    2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized to agarose gel
       ( Sp-2-AHA-cAMPS-Agarose )
       The protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer attached to position 2 of the ligand. The gel can be used for
       affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.
    A 069 0.6 ml, 2.5 ml, 6 ml  

    2'- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2'-AHC-cAMP-Agarose )
       The protein kinase A activator cyclic AMP immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2' position of the ligand. The gel
       can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'- ribose hydroxyl
       group such as some phosphodiesterases.
    A 058 0.6 ml, 2.5 ml, 6 ml  

    2'- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel
       ( Sp-2'-AHC-cAMPS-Agarose )
       The PDE-resistant protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2' position of the
       ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'-
       ribose hydroxyl group such as some phosphodiesterases.
    A 050 0.6 ml, 2.5 ml, 6 ml  

    2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 2'-AHC-cGMP-Agarose )
       The protein kinase G activator cyclic GMP immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'- position of the ligand. The
       gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'- ribose
       hydroxyl group, such as some phosphodiesterases.
       Kim & Park, J. Biochem. Mol. Biol., 36, 299 - 304 (2003); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
    A 059 0.6 ml, 2.5 ml, 6 ml  

    2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose gel ( Rp-2'-AHC-cGMPS-Agarose )
       The PDE-resistant PKG inhibitor Rp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'- position of the ligand. The
       gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'- ribose
       hydroxyl group such as some phosphodiesterases.
       Kim & Park, J. Biochem. Mol. Biol., 36, 299 - 304 (2003); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
    A 051 0.6 ml, 2.5 ml, 6 ml  

    2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel
       ( Sp-2'-AHC-cGMPS-Agarose )
       The PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'- position of the ligand. The
       gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'- ribose
       hydroxyl group such as some phosphodiesterases.
       Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).
    A 052 0.6 ml, 2.5 ml, 6 ml